Acute lymphoblastic leukemia in a child with a de novo germline gnb1 mutation

被引:21
作者
Brett, Maggie [1 ]
Lai, Angeline H. M. [2 ,3 ]
Ting, Teck-Wah [2 ,3 ]
Tan, Ah-Moy [3 ,4 ]
Foo, Roger [5 ]
Jamuar, Saumya [2 ,3 ]
Tan, Ene-Choo [1 ,3 ]
机构
[1] KK Womens & Childrens Hosp, Res Lab, 100 Bukit Timah Rd, Singapore 229899, Singapore
[2] KK Womens & Childrens Hosp, Genet Serv, Singapore, Singapore
[3] SingHlth Duke NUS Med Sch, Paediat Acad Clin Programme, Singapore, Singapore
[4] KK Womens & Childrens Hosp, Haematol Oncol Serv, Singapore, Singapore
[5] Genome Inst Singapore, Singapore, Singapore
基金
英国医学研究理事会;
关键词
G-PROTEIN; SUBUNITS;
D O I
10.1002/ajmg.a.38026
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:550 / 552
页数:3
相关论文
共 6 条
  • [1] Acute lymphoblastic leukemia in a child with a de novo germline gnb1 mutation
    Brett, Maggie
    Lai, Angeline H. M.
    Ting, Teck-Wah
    Tan, Ah-Moy
    Foo, Roger
    Jamuar, Saumya
    Tan, Ene-Choo
    [J]. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2017, 173 (02) : 550 - 552
  • [2] Molecular basis for interactions of G protein βγ subunits with effectors
    Ford, CE
    Skiba, NP
    Bae, HS
    Daaka, YH
    Reuveny, E
    Shekter, LR
    Rosal, R
    Weng, GZ
    Yang, CS
    Iyengar, R
    Miller, RJ
    Jan, LY
    Lefkowitz, RJ
    Hamm, HE
    [J]. SCIENCE, 1998, 280 (5367) : 1271 - 1274
  • [3] The 2.0 angstrom crystal structure of a heterotrimeric G protein
    Lambright, DG
    Sondek, J
    Bohm, A
    Skiba, NP
    Hamm, HE
    Sigler, PB
    [J]. NATURE, 1996, 379 (6563) : 311 - 319
  • [4] The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
    O'Hayre, Morgan
    Vazquez-Prado, Jose
    Kufareva, Irina
    Stawiski, Eric W.
    Handel, Tracy M.
    Seshagiri, Somasekar
    Gutkind, J. Silvio
    [J]. NATURE REVIEWS CANCER, 2013, 13 (06) : 412 - 424
  • [5] Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures
    Petrovski, Slave
    Kury, Sebastien
    Myers, Candace T.
    Anyane-Yeboa, Kwame
    Cogne, Benjamin
    Bialer, Martin
    Xia, Fan
    Hemati, Parisa
    Riviello, James
    Mehaffey, Michele
    Besnard, Thomas
    Becraft, Emily
    Wadley, Alexandrea
    Politi, Anya Revah
    Colombo, Sophie
    Zhu, Xiaolin
    Ren, Zhong
    Andrews, Ian
    Dudding-Byth, Tracy
    Schneider, Amy L.
    Wallace, Geoffrey
    Rosen, Aaron B. I.
    Schelley, Susan
    Enns, Gregory M.
    Corre, Pierre
    Dalton, Joline
    Mercier, Sandra
    Latypova, Xenia
    Schmitt, Sebastien
    Guzman, Edwin
    Moore, Christine
    Bier, Louise
    Heinzen, Erin L.
    Karachunski, Peter
    Shur, Natasha
    Grebe, Theresa
    Basinger, Alice
    Nguyen, Joanne M.
    Bezieau, Stephane
    Wierenga, Klaas
    Bernstein, Jonathan A.
    Scheffer, Ingrid E.
    Rosenfeld, Jill A.
    Mefford, Heather C.
    Isidor, Bertrand
    Goldstein, David B.
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2016, 98 (05) : 1001 - 1010
  • [6] Mutations in G protein β subunits promote transformation and kinase inhibitor resistance
    Yoda, Akinori
    Adelmant, Guillaume
    Tamburini, Jerome
    Chapuy, Bjoern
    Shindoh, Nobuaki
    Yoda, Yuka
    Weigert, Oliver
    Kopp, Nadja
    Wu, Shuo-Chieh
    Kim, Sunhee S.
    Liu, Huiyun
    Tivey, Trevor
    Christie, Amanda L.
    Elpek, Kutlu G.
    Card, Joseph
    Gritsman, Kira
    Gotlib, Jason
    Deininger, Michael W.
    Makishima, Hideki
    Turley, Shannon J.
    Javidi-Sharifi, Nathalie
    Maciejewski, Jaroslaw P.
    Jaiswal, Siddhartha
    Ebert, Benjamin L.
    Rodig, Scott J.
    Tyner, Jeffrey W.
    Marto, Jarrod A.
    Weinstock, David M.
    Lane, Andrew A.
    [J]. NATURE MEDICINE, 2015, 21 (01) : 71 - 75