Cancer Risk in Transgender People

被引:26
作者
de Blok, Christel J. M. [1 ,2 ]
Dreijerink, Koen M. A. [1 ,2 ]
den Heijer, Martin [1 ,2 ]
机构
[1] Vrije Univ Amsterdam Med Ctr, Dept Internal Med, Amsterdam UMC, Amsterdam, Netherlands
[2] Vrije Univ Amsterdam Med Ctr, Amsterdam UMC, Ctr Expertise Gender Dysphoria, POB 7057, NL-1007 MB Amsterdam, Netherlands
关键词
Transgender; Cancer; Sex hormones; Sex differences; FEMALE TRANSSEXUAL PERSONS; PROSTATE-CANCER; LONG-TERM; BREAST-CANCER; SEX-DIFFERENCES; OVARIAN-CANCER; PROGESTERONE-RECEPTORS; CERVICAL-CANCER; ESTROGEN; MORTALITY;
D O I
10.1016/j.ecl.2019.02.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gender-affirming hormonal treatment (HT) in transgender people is considered safe in general, but the question regarding (long-term) risk on sex hormone-related cancer remains. Because the risk on certain types of cancer differs between men and women, and some of these differences are attributed to exposure to sex hormones, the cancer risk may be altered in transgender people receiving HT. Although reliable epidemiologic data are sparse, the available data will be discussed in this article. Furthermore, recommendations for cancer screening and prevention will be discussed as well as whether to withdraw HT at time of a cancer diagnosis.
引用
收藏
页码:441 / +
页数:14
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