Ribosomal DNA intracellular journey and the new upcoming ribosomal organelle

被引:0
作者
Stupar, M. [1 ]
Vidovic, V. [2 ]
Lukac, D. [2 ]
机构
[1] Univ Belgrade, Vinca Inst Nucl Sci, Dept Radiobiol & Mol Genet, Belgrade, Serbia
[2] Univ Novi Sad, Fac Agr, Dept Anim Sci, Novi Sad 21000, Serbia
来源
IRANIAN JOURNAL OF SCIENCE AND TECHNOLOGY TRANSACTION A-SCIENCE | 2015年 / 39卷 / A3期
关键词
Nucleolus; mitochondrion; gene transfer; ribosomal organelle; evolution; GENE; RNA; NUCLEOLUS;
D O I
暂无
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Human mitochondrial DNA (mtDNA) is 16,569 base pairs (bp) in length, coding for 37 genes. During the course of evolution, nearly all the genes expressing ribosomal proteins and ribosomal RNAs (rRNA) genes have been transferred from the mitochondria to the nucleus. However, mitochondrial DNA contains two ribosomal RNAs genes (12S and 16S), which have not yet transferred to the nucleus. These two, should, soon or later, end up in the nucleus. What does the future likely hold for these genes? In the nucleus everything has already been prepared, since all of the ribosomal protein genes are now chromosomally encoded, and nucleolar organizers, the nucleolus, and 45 rDNA are developed waiting for 12S rRNA and I6S rRNA genes to join them, thus enabling the formation of the third DNA-containing organelle, the ribosomal compartment. What could be the reason for this major event in the existence of life on Earth as it is currently understood? The advent of the ribosomal organelle will likely have an enormous impact on reproductive characteristics and on intellectual (thoughts, abstract and complex ideas, imagination, dreams, spirit) activity of the brain. Could this be the answer to the question: Are humans still evolving?
引用
收藏
页码:267 / 272
页数:6
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