Laschiatrion, a new antifungal agent from a Favolaschia species (Basidiomycetes) active against human pathogens

被引：10

作者：

Anke, T ^{[1
]}

Werle, A

Kappe, RB

Sterner, O

机构：

[1] Inst Biotechnol & Drug Res IBWF eV, D-67663 Kaiserslautern, Germany

[2] Haema AG, Helios Med Ctr, D-99089 Erfurt, Germany

[3] Lund Univ, Dept Organ & Bioorgan Chem, S-22100 Lund, Sweden

来源：

JOURNAL OF ANTIBIOTICS | 2004年 / 57卷 / 08期

关键词：

D O I：

10.7164/antibiotics.57.496

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Laschiatrion (1), a new antifungal antibiotic, was isolated from fermentations of Favolaschia sp. 87129. (1) exhibits broad in vitro activity against several human pathogens while no antibacterial and cytotoxic activities could be detected. The structure was elucidated by spectroscopic techniques. As to our knowledge laschiatrion possesses a new steroid skeleton.

引用

页码：496 / 501

页数：6

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