Synthetic Applications of Intramolecular Aza-Wittig Reaction for the Preparation of Heterocyclic Compounds

被引：81
作者：
Palacios, Francisco
Aparicio, Domitila
Rubiales, Gloria
Alonso, Concepcion
de los Santos, Jesus M.
机构：
[1] Departamento de Química Orgónica I, Facultad de Farmacia, Universidad del País Vasco, Madrid 01080
来源：
CURRENT ORGANIC CHEMISTRY | 2009年 / 13卷 / 08期
关键词：
NITROGEN-CONTAINING HETEROCYCLES; USEFUL BUILDING-BLOCKS; SOLID-PHASE SYNTHESIS; 1ST TOTAL-SYNTHESIS; NATURAL-PRODUCTS; FACILE SYNTHESIS; RING-SYSTEMS; 1,4-BENZODIAZEPIN-5-ONE DERIVATIVES; ENANTIOSELECTIVE SYNTHESIS; 5-AZAAZULENE DERIVATIVES;
D O I：
10.2174/138527209788167196
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A review focused on recent advances in intramolecular aza-Wittig reaction of phosphazenes with several carbonyl or analogous compounds is reported. Phosphazenes afford intramolecular aza-Wittig reaction with different groups within the molecule as aldehydes, ketones, esters, thioesters, amides, anhydrides and sulfimides. One of the most important applications of this reaction is the synthesis of a wide range of heterocyclic compounds, ranging from simple monocyclic compounds to complex polycyclic and macrocyclic systems.
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页码：810 / 828
页数：19
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