Oncogene-induced cell senescence - Halting on the road to cancer

被引：278
作者：
Mooi, W. J.
Peeper, D. S.
机构：
[1] Vrije Univ Amsterdam, Med Ctr, Dept Pathol, NL-1081 HV Amsterdam, Netherlands
[2] Netherlands Canc Inst, Div Mol Genet, NL-1066 CX Amsterdam, Netherlands
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2006年 / 355卷 / 10期
关键词：
D O I：
10.1056/NEJMra062285
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：1037 / 1046
页数：10
相关论文
共 84 条
[1]  
Alrawi SJ, 2006, ANTICANCER RES, V26, P107
[2]   DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis [J].
Bartkova, J ;
Horejsi, Z ;
Koed, K ;
Krämer, A ;
Tort, F ;
Zieger, K ;
Guldberg, P ;
Sehested, M ;
Nesland, JM ;
Lukas, C ;
Orntoft, T ;
Lukas, J ;
Bartek, J .
NATURE, 2005, 434 (7035) :864-870
[3]   Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features [J].
Bastian, BC ;
LeBoit, PE ;
Pinkel, D .
AMERICAN JOURNAL OF PATHOLOGY, 2000, 157 (03) :967-972
[4]   Reversal of human cellular senescence:: roles of the p53 and p16 pathways [J].
Beauséjour, CM ;
Krtolica, A ;
Galimi, F ;
Narita, M ;
Lowe, SW ;
Yaswen, P ;
Campisi, J .
EMBO JOURNAL, 2003, 22 (16) :4212-4222
[5]   Human melanocyte senescence and melanoma susceptibility genes [J].
Bennett, DC .
ONCOGENE, 2003, 22 (20) :3063-3069
[6]   A large-scale RNAi screen in human cells identifies new components of the p53 pathway [J].
Berns, K ;
Hijmans, EM ;
Mullenders, J ;
Brummelkamp, TR ;
Velds, A ;
Heimerikx, M ;
Kerkhoven, RM ;
Madiredjo, M ;
Nijkamp, W ;
Weigelt, B ;
Agami, R ;
Ge, W ;
Cavet, G ;
Linsley, PS ;
Beijersbergen, RL ;
Bernards, R .
NATURE, 2004, 428 (6981) :431-437
[7]   Oncogene-induced senescence as an initial barrier in lymphoma development [J].
Braig, M ;
Lee, S ;
Loddenkemper, C ;
Rudolph, C ;
Peters, AHFM ;
Schlegelberger, B ;
Stein, H ;
Dörken, B ;
Jenuwein, T ;
Schmitt, CA .
NATURE, 2005, 436 (7051) :660-665
[8]   Tumor suppressors and oncogenes in cellular senescence [J].
Bringold, F ;
Serrano, M .
EXPERIMENTAL GERONTOLOGY, 2000, 35 (03) :317-329
[9]   Cellular senescence as a tumor-suppressor mechanism [J].
Campisi, J .
TRENDS IN CELL BIOLOGY, 2001, 11 (11) :S27-S31
[10]   Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors [J].
Campisi, J .
CELL, 2005, 120 (04) :513-522
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