Parallel Parkin: Cdc20 Takes a New Partner

被引:0
作者
Meza-Gutierrez, Fernando [1 ]
Hundley, Frances V. [1 ]
Toczyski, David P. [1 ]
机构
[1] Univ Calif San Francisco, Dept Biochem, San Francisco, CA 94143 USA
关键词
ANAPHASE-PROMOTING COMPLEX;
D O I
10.1016/j.molcel.2015.09.015
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
CDC20 and CDH1 are well-established substrate receptors for the Anaphase Promoting Complex/Cyclosome (APC/C). In this issue of Molecular Cell, Lee et al. (2015) show that these adaptors can also target cell cycle proteins for destruction through a second ubiquitin ligase, Parkin.
引用
收藏
页码:3 / 4
页数:2
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