Flow microreactor synthesis in organo-fluorine chemistry

被引：50

作者：

Amii, Hideki ^{[1
]}

Nagaki, Aiichiro ^{[2
]}

Yoshida, Jun-ichi ^{[2
]}

机构：

[1] Gunma Univ, Grad Sch Sci & Technol, Div Mol Sci, Kiryu, Gunma 3768515, Japan

[2] Kyoto Univ, Grad Sch Engn, Dept Synthet & Biol Chem, Nishikyo Ku, Kyoto 6158510, Japan

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷

关键词：

defluorination; fluorine; fluorination; flow microreactor; organo-fluorine; perfluoroalkylation; ELEMENTAL FLUORINE; GAS-LIQUID; PHOTOCHROMIC DIARYLETHENES; MICROFLOW; GENERATION; OPTIMIZATION; TRIFLUORIDE; SYSTEMS; REACTOR;

D O I：

10.3762/bjoc.9.314

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organo-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties. Despite increased demand in wide fields of science, synthesis of fluoro-organic compounds is still often faced with problems such as the difficulties in handling of fluorinating reagents and in controlling of chemical reactions. Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. This review outlines the successful examples of synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems to overcome long-standing problems in fluorine chemistry.

引用

页码：2793 / 2802

页数：10

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