Hypothermia after Acute Ischemic Stroke

被引：30

作者：

Hemmen, Thomas M. ^{[1
]}

Lyden, Patrick D. ^{[1
,2
]}

机构：

[1] Univ Calif San Diego, Dept Neurosci, San Diego, CA 92103 USA

[2] Dept Vet Affairs, San Diego, CA USA

来源：

JOURNAL OF NEUROTRAUMA | 2009年 / 26卷 / 03期

关键词：

cerebral vascular disease; hypothermia; regeneration; stem cells; stroke; traumatic brain injury; traumatic spinal cord injury; CEREBRAL-ARTERY OCCLUSION; DELAYED POSTISCHEMIC HYPOTHERMIA; DAMAGE COOL AID; MILD HYPOTHERMIA; THERAPEUTIC HYPOTHERMIA; MODERATE HYPOTHERMIA; SHIVERING THRESHOLD; FOCAL ISCHEMIA; CARDIAC-ARREST; INFARCT SIZE;

D O I：

10.1089/neu.2008.0574

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Induced hypothermia after ischemic stroke is a promising neuroprotective therapy and is the most potent in preclinical models. Technological limitations and homeostatic mechanisms that maintain core body temperature, however, have limited the clinical application of hypothermia. Advances in intravascular cooling and successful trials of hypothermia after global cerebral ischemia, such as in cardiac arrest and neonatal asphyxia, have renewed interest in hypothermia for stroke.

引用

页码：387 / 391

页数：5

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