Conversion of titania (TiO2) into conductive titanium (Ti) nanotube arrays for combined drug-delivery and electrical stimulation therapy

被引：30
作者：
Gulati, Karan [1 ]
Maher, Shaheer [1 ,2 ]
Chandrasekaran, Soundarrajan [1 ,3 ]
Findlay, David M. [4 ]
Losic, Dusan [1 ]
机构：
[1] Univ Adelaide, Sch Chem Engn, Adelaide, SA 5005, Australia
[2] Assiut Univ, Fac Pharm, Assiut 71526, Egypt
[3] Univ S Australia, Mawson Inst, Adelaide, SA 5095, Australia
[4] Univ Adelaide, Discipline Orthopaed & Trauma, Adelaide, SA 5005, Australia
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2016年 / 4卷 / 03期
基金：
澳大利亚研究理事会;
关键词：
BONE; IMPLANTS; MAGNESIUM; CARRIERS; GROWTH; WIRES;
D O I：
10.1039/c5tb02108a
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
The conversion of titania (TiO2) nanotubes into titanium (Ti), while preserving their nanotubular structures, is demonstrated. Their application as bone implants and electrodes for combined local drug delivery and electrical stimulation therapy is proposed.
引用
收藏
页码：371 / 375
页数：5
相关论文
共 30 条
  • [1] Treatment of nonunions with electric and electromagnetic fields
    Aaron, RK
    Ciombor, DM
    Simon, BJ
    [J]. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2004, (419) : 21 - 29
  • [2] Non-eroding drug-releasing implants with ordered nanoporous and nanotubular structures: concepts for controlling drug release
    Aw, Moom Sinn
    Kurian, Mima
    Losic, Dusan
    [J]. BIOMATERIALS SCIENCE, 2014, 2 (01) : 10 - 34
  • [3] Characterization of drug-release kinetics in trabecular bone from titania nanotube implants
    Aw, Moom Sinn
    Khalid, Kamarul A.
    Gulati, Karan
    Atkins, Gerald J.
    Pivonka, Peter
    Findlay, David M.
    Losic, Dusan
    [J]. INTERNATIONAL JOURNAL OF NANOMEDICINE, 2012, 7 : 4883 - 4892
  • [4] Magnetic-responsive delivery of drug-carriers using titania nanotube arrays
    Aw, Moom Sinn
    Addai-Mensah, Jonas
    Losic, Dusan
    [J]. JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (14) : 6561 - 6563
  • [5] A multi-drug delivery system with sequential release using titania nanotube arrays
    Aw, Moom Sinn
    Addai-Mensah, Jonas
    Losic, Dusan
    [J]. CHEMICAL COMMUNICATIONS, 2012, 48 (27) : 3348 - 3350
  • [6] Chemical reduction of three-dimensional silica micro-assemblies into microporous silicon replicas
    Bao, Zhihao
    Weatherspoon, Michael R.
    Shian, Samuel
    Cai, Ye
    Graham, Phillip D.
    Allan, Shawn M.
    Ahmad, Gul
    Dickerson, Matthew B.
    Church, Benjamin C.
    Kang, Zhitao
    Abernathy, Harry W., III
    Summers, Christopher J.
    Liu, Meilin
    Sandhage, Kenneth H.
    [J]. NATURE, 2007, 446 (7132) : 172 - 175
  • [7] Silicon diatom frustules as nanostructured photoelectrodes
    Chandrasekaran, Soundarrajan
    Sweetman, Martin J.
    Kant, Krishna
    Skinner, William
    Losic, Dusan
    Nann, Thomas
    Voelcker, Nicolas H.
    [J]. CHEMICAL COMMUNICATIONS, 2014, 50 (72) : 10441 - 10444
  • [8] Cathodic voltage-controlled electrical stimulation of titanium implants as treatment for methicillin-resistant Staphylococcus aureus periprosthetic infections
    Ehrensberger, Mark T.
    Tobias, Menachem E.
    Nodzo, Scott R.
    Hansen, Lisa A.
    Luke-Marshall, Nicole R.
    Cole, Ross F.
    Wild, Linda M.
    Campagnari, Anthony A.
    [J]. BIOMATERIALS, 2015, 41 : 97 - 105
  • [9] Diameter of titanium nanotubes influences anti-bacterial efficacy
    Ercan, Batur
    Taylor, Erik
    Alpaslan, Ece
    Webster, Thomas J.
    [J]. NANOTECHNOLOGY, 2011, 22 (29)
  • [10] Decreased Staphylococcus aureus biofilm growth on anodized nanotubular titanium and the effect of electrical stimulation
    Ercan, Batur
    Kummer, Kim M.
    Tarquinio, Keiko M.
    Webster, Thomas J.
    [J]. ACTA BIOMATERIALIA, 2011, 7 (07) : 3003 - 3012
123