Ion channels and the control of blood pressure

被引:31
作者
Baker, EH [1 ]
机构
[1] Univ London St Georges Hosp, Sch Med, Dept Pharmacol & Clin Pharmacol, London SW17 0RE, England
关键词
Bartter's syndrome; blood pressure; epithelium; ion channels; Liddle's syndrome; vascular tone;
D O I
10.1046/j.1365-2125.2000.00159.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Ion channels exist in all cells and are enormously varied in structure, function and regulation. Some progress has been made in understanding the role that ion channels play in the control of blood pressure, but the discipline is still in its infancy. Ion channels provide many different targets for intervention in disorders of blood pressure and exciting advances have been made in this field. It is possible that new drugs, as well as antisense nucleotide technology or gene therapy directed towards ion channels, may form a new class of treatments for high and low blood pressure in the future.
引用
收藏
页码:185 / 198
页数:14
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