Mimicking a Superoxide Dismutase (SOD) Enzyme by copper(II) and zinc(II)-complexes

被引：5

作者：

Imre Labadi ^{[1
]}

Benkoe, Maria ^{[1
]}

Kata Marko ^{[1
]}

Istvan Szilagyi ^{[1
]}

机构：

[1] Univ Szeged, Dept Inorgan & Analyt Chem, H-6720 Szeged, Hungary

来源：

REACTION KINETICS AND CATALYSIS LETTERS | 2009年 / 96卷 / 02期

关键词：

SOD enzyme; mimicking enzymes; copper-zinc complexes; II-NI-II; IMIDAZOLATE-BRIDGED COMPLEXES; ELECTRON-SPIN-RESONANCE; PARAMAGNETIC-RESONANCE; PLAUSIBLE MODEL; CAPPING LIGAND; CU-II; ZN-II; BINUCLEATING MACROCYCLE; MANGANESE CATALASE;

D O I：

10.1007/s11144-009-5526-4

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Mimicking the Superoxide Dismutase Enzyme (SOD), several imidazolato-bridged copper(II)-zinc(II) complexes were prepared, characterised by IR spectroscopy and their SOD enzyme activity was determined. 2,2'-Bipyridine, 2,2':6',2aEuro(3)-terpyridine and tris(2-aminoethyl)amine molecules were used on both metal sides, as coordinating ligands. The complex, containing the 2,2':6',2aEuro(3)-terpyridine ligand on copper side has the smallest SOD activity, which indicates the importance of the rigidity of the copper complex in SOD activity.

引用

页码：327 / 333

页数：7

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