Treatment of bone and joint infections caused by Enterobacter cloacae with a fluoroquinolone-cotrimoxazole combination

被引：8
作者：
Cisse, Hawa [1 ]
Vernet-Garnier, Veronique [2 ]
Hentzien, Maxime [1 ]
Bajolet, Odile [3 ]
Lebrun, Delphine [4 ]
Bonnet, Morgane [5 ]
Ohl, Xavier [6 ]
Diallo, Saidou [6 ]
Bani-Sadr, Firouze [1 ]
机构：
[1] Reims Teaching Hosp, Dept Internal Med & Infect Dis, Reims, France
[2] Reims Teaching Hosp, Dept Bacteriol, Reims, France
[3] Reims Teaching Hosp, Dept Hyg, Reims, France
[4] Manchester Hosp, Dept Internal Med & Infect Dis, Charleville Mezieres, France
[5] Reims Teaching Hosp, Dept Pharm, Reims, France
[6] Reims Teaching Hosp, Dept Orthopaed Surg, Reims, France
来源：
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2019年 / 54卷 / 02期
关键词：
Bone infection; Enterobacter spp; Enterobacter cloacae; Fluoroquinolone-cotrimoxazole combination; Fluoroquinolone; Cotrimoxazole; GRAM-NEGATIVE BACILLI; RISK-FACTORS; TRIMETHOPRIM; OSTEOMYELITIS; RIFAMPIN; THERAPY;
D O I：
10.1016/j.ijantimicag.2019.05.010
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Although the frequency of bone and joint infections caused by Enterobacter spp. is increasing, studies regarding the optimal antibiotic therapy are scarce. The objective of this retrospective study was to assess the clinical outcomes and safety of a fluoroquinolone-cotrimoxazole combination for the treatment of bone and joint infections caused by Enterobacter cloacae. Between 2010 and 2017, 30 patients with bone and joint infections caused by E. cloacae were treated with a fluoroquinolone-cotrimoxazole combination for 8-12 weeks. There were 26 cases (87%) of infection of an internal fixation device, two cases (6.6%) of pseudarthrosis with chronic osteomyelitis, and two cases (6.6%) of infection of knee and ankle prosthetic devices. The cure rate of the fluoroquinolone-cotrimoxazole combination was 80% by intention-to-treat analysis, with a mean follow-up of 29.3 +/- 19.1 months. The fluoroquinolone-cotrimoxazole combination for 8-12 weeks is effective for the treatment of bone and joint infections caused by E. cloacae. (C) 2019 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码：245 / 248
页数：4
相关论文
共 50 条
  • [41] Daptomycin for treatment of patients with bone and joint infections: a systematic review of the clinical evidence
    Falagas, Matthew E.
    Giannopoulou, Konstantina P.
    Ntziora, Fotinie
    Papagelopoulos, Panayiotis J.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 30 (03) : 202 - 209
  • [42] Significance of Negative Cultures in the Treatment of Acute Hematogenous Bone and Joint Infections in Children
    Paakkonen, Markus
    Kallio, Markku J. T.
    Kallio, Pentti E.
    Peltola, Heikki
    JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2013, 2 (02) : 119 - 125
  • [43] Rapid and aggressive treatment the key to successful management of bone and joint infections in the elderly
    不详
    Drugs & Therapy Perspectives, 2001, 17 (4) : 6 - 8
  • [44] Telavancin for the treatment of methicillin-resistant Staphylococcus aureus bone and joint infections
    Harting, Julie
    Fernandez, Francisco
    Kelley, Rob
    Wiemken, Tim
    Peyrani, Paula
    Ramirez, Julio
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2017, 89 (04) : 294 - 299
  • [45] Improved Diagnosis and Treatment of Bone and Joint Infections Using an Evidence-based Treatment Guideline
    Quick, Rachel D.
    Williams, John
    Fernandez, Marisol
    Gottschalk, Hilton
    Cosgrove, Peter
    Kahlden, Kyle
    Merkel, Kathryn
    Thoreson, Lynn
    Boswell, Patrick
    Hauger, Sarmistha B.
    JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2018, 38 (06) : E354 - E359
  • [46] Efficacy and safety of colistin plus beta-lactams for bone and joint infection caused by fluoroquinolone-resistant gram-negative bacilli: a prospective multicenter study
    Mancheno-Losa, Mikel
    Murillo, Oscar
    Benavent, Eva
    Sorli, Luisa
    Riera, Melchor
    Cobo, Javier
    Benito, Natividad
    Morata, Laura
    Ribera, Alba
    Sobrino, Beatriz
    Fernandez-Sampedro, Marta
    Munez, Elena
    Bahamonde, Alberto
    Barbero, Jose Maria
    del Toro, M. Dolores
    Villa, Jenifer
    Rigo-Bonnin, Raul
    Luque, Sonia
    Garcia-Luque, Isabel
    Oliver, Antonio
    Esteban, Jaime
    Lora-Tamayo, Jaime
    INFECTION, 2025, 53 (01) : 359 - 372
  • [47] Repeated Serum Alkaline Phosphatase Measurements in the Treatment of Childhood Acute Bone and Joint Infections with High Doses of Antibiotics
    Paakkonen, Markus
    Kallio, Markku J. T.
    Kallio, Pentti E.
    Peltola, Heikki
    ANNALS OF LABORATORY MEDICINE, 2013, 33 (05) : 375 - 378
  • [48] Pediatric bone and joint infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus
    Dohin, Bruno
    Gillet, Yves
    Kohler, Remi
    Lina, Gerard
    Vandenesch, Francois
    Vanhems, Philippe
    Floret, Daniel
    Etienne, Jerome
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2007, 26 (11) : 1042 - 1048
  • [49] Impact of a pediatric infectious disease consultation service on timely step-down to oral antibiotic treatment for bone and joint infections
    Mehler, Katrin
    Oberthuer, Andre
    Yagdiran, Ayla
    Butzer, Sarina
    Jung, Norma
    INFECTION, 2023, 51 (04) : 831 - 838
  • [50] Treatment Outcomes in Infections Caused by "SPICE" (Serratia, Pseudomonas, Indole-positive Proteus, Citrobacter, and Enterobacter) Organisms: Carbapenem versus Noncarbapenem Regimens
    Moy, Stanley
    Sharma, Roopali
    CLINICAL THERAPEUTICS, 2017, 39 (01) : 170 - 176
12345