Extensive Testing and Public Health Interventions for the Control of COVID-19 in the Republic of Cyprus between March and May 2020

被引:23
作者
Quattrocchi, Annalisa [1 ]
Mamais, Ioannis [2 ]
Tsioutis, Constantinos [3 ]
Christaki, Eirini [4 ]
Constantinou, Costas [5 ]
Koliou, Maria [4 ]
Pana, Zoi-Dorothea [3 ]
Silvestros, Valentinos [6 ]
Theophanous, Fani [6 ]
Haralambous, Christos [6 ]
Stylianou, Androulla [6 ]
Sotiriou, Sotiroula [6 ]
Athanasiadou, Maria [7 ]
Kyprianou, Theopisti [7 ]
Demetriou, Anna [7 ]
Demetriou, Christiana A. [1 ]
Kolokotroni, Ourania [1 ]
Gregoriou, Ioanna [6 ]
Paphitou, Niki [8 ]
Panos, George [4 ,9 ]
Kostrikis, Leontios [10 ]
Karayiannis, Peter [11 ]
Petrikkos, Georgios [3 ]
Agathangelou, Petros [12 ]
Mixides, George [8 ]
Siakallis, Georgios [11 ,13 ]
Hadjihannas, Linos [5 ]
Palazis, Lakis [5 ]
Vavlitou, Anna [5 ]
Matsentidou-Timiliotou, Chrystalla [14 ]
Koukios, Dimitris [14 ]
Adamidi, Tonia [5 ]
Frangopoulos, Frangiskos [5 ]
Constantinou, Elizabeth [6 ]
Nikolopoulos, Georgios [4 ]
机构
[1] Univ Nicosia, Dept Primary Care & Populat Hlth, Med Sch, CY-1700 Nicosia, Cyprus
[2] European Univ, Sch Sci, CY-1516 Nicosia, Cyprus
[3] European Univ, Sch Med, CY-1516 Nicosia, Cyprus
[4] Univ Cyprus, Med Sch, CY-1678 Nicosia, Cyprus
[5] Nicosia Gen Hosp, CY-1678 Nicosia, Cyprus
[6] Minist Hlth, Unit Surveillance & Control Communicable Dis, CY-1448 Nicosia, Cyprus
[7] Minist Hlth, Hlth Monitoring Unit, CY-1448 Nicosia, Cyprus
[8] Amer Med Ctr, CY-1311 Nicosia, Cyprus
[9] Univ Patras, Patras Univ Gen Hosp, Dept Internal Med, Div Infect Dis,Med Sch, Patras 26504, Greece
[10] Univ Cyprus, Dept Biol Sci, CY-1678 Nicosia, Cyprus
[11] Univ Nicosia, Dept Basic & Clin Sci, Med Sch, CY-1700 Nicosia, Cyprus
[12] Nicosia Heart Inst, Heart & Med Ctr, CY-2410 Nicosia, Cyprus
[13] Larnaca Gen Hosp, CY-6301 Larnax, Cyprus
[14] Limassol Gen Hosp, CY-3304 Limassol, Cyprus
关键词
surveillance; COVID-19; pandemic; contact tracing; containment measures; Cyprus;
D O I
10.3390/jcm9113598
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Coronavirus disease 2019 (COVID-19) has significantly affected the well-being of individuals worldwide. We herein describe the epidemiology of COVID-19 in the Republic of Cyprus during the first epidemic wave (9 March-3 May 2020). We analyzed surveillance data from laboratory-confirmed cases, including targeted testing and population screening. Statistical analyses included logistic regression. During the surveillance period, 64,136 tests (7322.3 per 100,000) were performed, 873 COVID-19 cases were diagnosed, and 20 deaths were reported (2.3%). Health-care workers (HCWs) represented 21.4% of cases. Overall, 19.1% of cases received hospital care and 3.7% required admission to Intensive Care Units. Male sex (adjusted Odds Ratio (aOR): 3.04; 95% Confidence Interval (CI): 1.97-4.69), increasing age (aOR: 1.56; 95%CI: 1.36-1.79), symptoms at diagnosis (aOR: 6.05; 95%CI: 3.18-11.50), and underlying health conditions (aOR: 2.08; 95%CI: 1.31-3.31) were associated with hospitalization. For recovered cases, the median time from first to last second negative test was 21 days. Overall, 119 primary cases reported 616 close contacts, yielding a pooled secondary attack rate of 12% (95%CI: 9.6-14.8%). Three population-based screening projects, and two projects targeting employees and HCWs, involving 25,496 people, revealed 60 positive individuals (0.2%). Early implementation of interventions with targeted and expanded testing facilitated prompt outbreak control on the island.
引用
收藏
页码:1 / 13
页数:13
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