Fluoroaromatic universal bases in peptide nucleic acids

被引：22

作者：

Frey, KA ^{[1
]}

Woski, SA ^{[1
]}

机构：

[1] Univ Alabama, Dept Chem, Tuscaloosa, AL 35487 USA

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 19期

关键词：

D O I：

10.1039/b205734d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluoroaromatic peptide nucleic acid residues were found to possess little base discrimination when incorporated into PNA.DNA double helices.

引用

页码：2206 / 2207

页数：2

共 23 条

[1] Analysing genetic information with DNA arrays [J].

Case-Green, SC ;

Mir, KU ;

Pritchard, CE ;

Southern, EM .

CURRENT OPINION IN CHEMICAL BIOLOGY, 1998, 2 (03) :404-410

[2] Nitroazole universal bases in peptide nucleic acids [J].

Challa, H ;

Styers, ML ;

Woski, SA .

ORGANIC LETTERS, 1999, 1 (10) :1639-1641

[3] Incorporation and characterization of abasic and phenyl residues in peptide nucleic acids [J].

Challa, H ;

Woski, SA .

TETRAHEDRON LETTERS, 1999, 40 (48) :8333-8336

[4] INTERACTION BETWEEN STACKED ARYL GROUPS IN 1,8-DIARYLNAPHTHALENES - DOMINANCE OF POLAR/PI OVER CHARGE-TRANSFER EFFECTS [J].

COZZI, F ;

SIEGEL, JS .

PURE AND APPLIED CHEMISTRY, 1995, 67 (05) :683-689

[5] POLAR INTERACTIONS BETWEEN STACKED PI-SYSTEMS IN FLUORINATED 1,8-DIARYLNAPHTHALENES - IMPORTANCE OF QUADRUPOLE-MOMENTS IN MOLECULAR RECOGNITION [J].

COZZI, F ;

PONZINI, F ;

ANNUNZIATA, R ;

CINQUINI, M ;

SIEGEL, JS .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (09) :1019-1020

[6] PNA HYBRIDIZES TO COMPLEMENTARY OLIGONUCLEOTIDES OBEYING THE WATSON-CRICK HYDROGEN-BONDING RULES [J].

EGHOLM, M ;

BUCHARDT, O ;

CHRISTENSEN, L ;

BEHRENS, C ;

FREIER, SM ;

DRIVER, DA ;

BERG, RH ;

KIM, SK ;

NORDEN, B ;

NIELSEN, PE .

NATURE, 1993, 365 (6446) :566-568

[7] Advances in fluorescent in situ hybridisation [J].

Ekong, R ;

Wolfer, J .

CURRENT OPINION IN BIOTECHNOLOGY, 1998, 9 (01) :19-24

[8]

FREY KA, UNPUB

[9] Peptide-nucleic acids (PNAs): A tool for the development of gene expression modifiers [J].

Gambari, R .

CURRENT PHARMACEUTICAL DESIGN, 2001, 7 (17) :1839-1862

[10] Peptide nucleic acids (PNA): Synthesis, properties and potential applications [J].

Hyrup, B ;

Nielsen, PE .

BIOORGANIC & MEDICINAL CHEMISTRY, 1996, 4 (01) :5-23

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