Minor steroidal alkaloids from the marine sponge Corticium sp.

被引：25

作者：

Borbone, N

De Marino, S

Iorizzi, M

Zollo, FO

Debitus, C

Esposito, G

Iuvone, T

机构：

[1] Univ Naples Federico II, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy

[2] Univ Molise, Dipartimento Sci & Tecnol Agrpalimentari Ambienta, I-86100 Campobasso, Italy

[3] Ctr Noumea, IRD, Noumea 98848, New Caledonia

[4] Univ Naples Federico II, Dipartimento Farmacol Sperimentale, I-80131 Naples, Italy

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 08期

关键词：

D O I：

10.1021/np020027r

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new steroidal alkaloids, plakinamine G (1), plakinamine II (2), 4alpha hydroxydemethylplakinamine B (3), and tetrahydroplakinanune A (4), along with three known compound,, were isolated front the marine sponge Corticum sp The structures, of these metabolites were elucidated largely by 1D and 2D NMR methods and accurate mass measurements (HR-EIMS) Compound 1 2 and 4 show significant in vitro cytotoxicity.

引用

页码：1206 / 1209

页数：4

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