Enantioselective synthesis and application of the highly fluorescent and environment-sensitive amino acid 6-(2-dimethylaminonaphthoyl) alanine (DANA)

被引：60

作者：

Nitz, M ^{[1
]}

Mezo, AR ^{[1
]}

Ali, MH ^{[1
]}

Imperiali, B ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 17期

关键词：

D O I：

10.1039/b205224e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

6-(2-Dimethylaminonaphthoyl) alanine (DANA) was prepared via an enantioselective synthesis and incorporated into the S-peptide of RNase S establishing the large changes in fluorescence that can occur upon peptide-protein interaction.

引用

页码：1912 / 1913

页数：2

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