Functional duality of the cell wall

被引：102

作者：

Latge, Jean-Paul ^{[1
]}

Beauvais, Anne ^{[1
]}

机构：

[1] Inst Pasteur, Unite Aspergillus, Paris, France

来源：

CURRENT OPINION IN MICROBIOLOGY | 2014年 / 20卷

关键词：

ASPERGILLUS-FUMIGATUS; BIOSYNTHESIS; ARCHITECTURE; RECOGNITION; RESISTANCE;

D O I：

10.1016/j.mib.2014.05.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The polysaccharide cell wall is the extracellular armour of the fungal cell. Although essential in the protection of the fungal cell against aggressive external stresses, the biosynthesis of the polysaccharide core is poorly understood. For a long time it was considered that this cell wall skeleton was a fixed structure whose role was only to be sensed as non-self by the host and consequently trigger the defence response. It is now known that the cell wall polysaccharide composition and localization continuously change to adapt to their environment and that these modifications help the fungus to escape from the immune system. Moreover, cell wall polysaccharides could function as true virulence factors.

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页码：111 / 117

页数：7

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