Cu(I)-promoted one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from anti-3-aryl-2,3-dibromopropanoic acids and nitrobenzaldehydes

被引:4
|
作者
Liu, Xia [1 ]
Su, Changhui [2 ]
机构
[1] Jiangsu Open Univ, Coll Environm & Ecol, Nanjing 210036, Jiangsu, Peoples R China
[2] Nanjing Univ, Jinling Coll, Sch Chem & Life Sci, Nanjing, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
1,2,3-triazoles; anti-3-aryl-2,3-dibromopropanoic acid; click chemistry; one-pot; STEREOSELECTIVE-SYNTHESIS; TERMINAL ALKYNES; AZIDES; CYCLOADDITION;
D O I
10.1080/00397911.2016.1262039
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of 1,4-disubstituted 1,2,3-triazoles were synthesized through a one-pot process from easily available anti-3-aryl-2,3-dibromopropanoic acids and nitrobenzaldehydes in hexamethylphosphoric triamide. Inexpensive copper(I) iodide was the catalyst.
引用
收藏
页码:279 / 284
页数:6
相关论文
共 50 条
  • [41] Efficient synthesis, antitubercular and antimicrobial evaluation of 1,4-disubstituted 1,2,3-triazoles with amide functionality
    Kaushik, C. P.
    Pahwa, Ashima
    Singh, Dharmendra
    Kumar, Krishan
    Luxmi, Raj
    MONATSHEFTE FUR CHEMIE, 2019, 150 (06): : 1127 - 1136
  • [42] Recent Catalysts Used in the Synthesis of 1,4-Disubstituted 1,2,3-Triazoles by Heterogeneous and Homogeneous Methods
    Noriega, Saul
    Leyva, Elisa
    Moctezuma, Edgar
    Flores, Luisa
    Loredo-Carrillo, Silvia
    CURRENT ORGANIC CHEMISTRY, 2020, 24 (05) : 536 - 549
  • [43] Regioselective one-pot synthesis of 1,4-disubstituted 1,2,3-triazole derivatives
    Gumus, Aysegul
    Ucur, Sibel
    HETEROCYCLIC COMMUNICATIONS, 2014, 20 (06) : 361 - 364
  • [44] Recyclable clay supported Cu (II) catalyzed tandem one-pot synthesis of 1-aryl-1,2,3-triazoles
    Mohammed, Shabber
    Padala, Anil K.
    Dar, Bashir A.
    Singh, Baldev
    Sreedhar, B.
    Vishwakarma, Ram A.
    Bharate, Sandip B.
    TETRAHEDRON, 2012, 68 (39) : 8156 - 8162
  • [45] Synthesis, in vitro and computational studies of 1,4-disubstituted 1,2,3-triazoles as potential α-glucosidase inhibitors
    Jabeen, Farukh
    Shehzadi, Syeda Aaliya
    Fatmi, Muhammad Qaiser
    Shaheen, Sobia
    Iqbal, Lubna
    Afza, Nighat
    Panda, Siva S.
    Ansari, Farzana Latif
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (03) : 1029 - 1038
  • [46] Design, synthesis, anticancer and antioxidant activities of amide linked 1,4-disubstituted 1,2,3-triazoles
    Kaushik, C. P.
    Sangwan, Jyoti
    Luxmi, Raj
    Kumar, Devinder
    Kumar, Deepak
    Das, Ashutosh
    Kumar, Ashwani
    Singh, Dharmendra
    JOURNAL OF MOLECULAR STRUCTURE, 2021, 1226
  • [47] One-Pot Synthesis of 1-Monosubstituted 1,2,3-Triazoles from Propargyl Alcohol
    Han, Chunmei
    Dong, Suping
    Zhang, Wensheng
    Chen, Zhen
    SYNLETT, 2018, 29 (05) : 673 - 677
  • [48] Synthesis of 1,4-disubstituted 1,2,3-triazoles based on cobalt bis(1,2-dicarbollide)
    Kosenko, I. D.
    Lobanova, I. A.
    Chekulaeva, L. A.
    Godovikov, I. A.
    Bregadze, V. I.
    RUSSIAN CHEMICAL BULLETIN, 2013, 62 (02) : 497 - 503
  • [49] CTAB promoted CuI catalyzed green and economical synthesis of 1,4-disubstituted-1,2,3-triazoles
    Ali, Abdul Aziz
    Sharma, Rahul
    Saikia, Prakash J.
    Sarma, Diganta
    SYNTHETIC COMMUNICATIONS, 2018, 48 (10) : 1206 - 1212
  • [50] Base-mediated reaction of vinyl bromides with aryl azides: one-pot synthesis of 1,5-disubstituted 1,2,3-triazoles
    Wu, Luyong
    Chen, Yuxue
    Luo, Jianheng
    Sun, Qi
    Peng, Mingsheng
    Lin, Qiang
    TETRAHEDRON LETTERS, 2014, 55 (29) : 3847 - 3850