Total synthesis of (-)-clavosolide A

被引：20

作者：

Chakraborty, Tushar Kanti ^{[1
]}

Reddy, Vakiti Ramkrishna ^{[1
]}

Chattopadhyay, Anut Kumar ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 42期

关键词：

clavosolides; clavosolide A; epoxide opening; 2-methyl-1,3-diol; diolide;

D O I：

10.1016/j.tetlet.2006.08.055

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (-)-clavosolide A is achieved employing a radical-mediated route to build the substituted tetrahydropyran unit, a Yamaguchi reaction to construct the diolide aglycon and the Schmidt method for the final glycosidation step. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：7435 / 7438

页数：4

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