Development of a Compton Camera for Online Range Monitoring of Laser-Accelerated Proton Beams via Prompt-Gamma Detection

被引：15

作者：

Thirolf, P. G. ^{[1
]}

Lang, C. ^{[1
]}

Aldawood, S. ^{[1
,2
]}

v.d. Kolff, H. G. ^{[1
,4
]}

Maier, L. ^{[3
]}

Schaart, D. R. ^{[4
]}

Parodi, K. ^{[1
]}

机构：

[1] Univ Munich, Fac Phys, Garching, Germany

[2] King Saud Univ, Riyadh, Saudi Arabia

[3] Tech Univ Munich, Phys Dept E12, Garching, Germany

[4] Delft Univ Technol, Delft, Netherlands

来源：

INPC 2013 - INTERNATIONAL NUCLEAR PHYSICS CONFERENCE, VOL. 2 | 2014年 / 66卷

关键词：

VERIFICATION;

D O I：

10.1051/epjconf/20146611036

中图分类号：

P1 [天文学];

学科分类号：

0704 ;

摘要：

Presently large efforts are conducted in Munich towards the development of proton beams for bio-medical applications, generated via the technique of particle acceleration from high-power, short-pulse lasers. While so far mostly offline diagnostics tools are used in this context, we aim at developing a reliable and accurate online range monitoring technique, based on the position-sensitive detection of prompt gamma rays emitted from nuclear reactions between the proton beam and the biological sample. For this purpose, we develop a Compton camera, designed to be able to track not only the Compton scattering of the primary photon, but also to detect the secondary Compton electron, thus reducing the Compton cone to an arc segment and by this increasing the source reconstruction efficiency. Design specifications and the status of the protype system are discussed.

引用

页数：4

共 15 条

[1]

Beusch W., 1994, CERNECP9417

[2] Charged hadron tumour therapy monitoring by means of PET [J].

Enghardt, W ;

Crespo, P ;

Fiedler, F ;

Hinz, R ;

Parodi, K ;

Pawelke, J ;

Pönisch, F .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2004, 525 (1-2) :284-288

[3]

Fiedler F., 2011, NUCL SCI S C REC NSS

[4] Optimisation of a dual head semiconductor Compton camera using Geant4 [J].

Harkness, L. J. ;

Boston, A. J. ;

Boston, H. C. ;

Cooper, R. J. ;

Cresswell, J. R. ;

Grint, A. N. ;

Nolan, P. J. ;

Oxley, D. C. ;

Scraggs, D. P. ;

Beveridge, T. ;

Gillam, J. ;

Lazarus, I. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2009, 604 (1-2) :351-354

[5] A Compton imager for in-vivo dosimetry of proton beams-A design study [J].

Kormoll, T. ;

Fiedler, F. ;

Schoene, S. ;

Wuestemann, J. ;

Zuber, K. ;

Enghardt, W. .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2011, 626 :114-119

[6] Prompt gamma detection for range verification in proton therapy [J].

Kurosawa, Shunsuke ;

Kubo, Hidetoshi ;

Ueno, Kazuki ;

Kabuki, Shigeto ;

Iwaki, Satoru ;

Takahashi, Michiaki ;

Taniue, Kojiro ;

Higashi, Naoki ;

Miuchi, Kentaro ;

Tanimori, Toru ;

Kim, Dogyun ;

Kim, Jongwon .

CURRENT APPLIED PHYSICS, 2012, 12 (02) :364-368

[7]

Lang C, 2012, RADIOTHER ONCOL, V102, pS30

[8]

Lojacono X., 2011, NUCL SCI S C REC, V1, P3518

[9] Prompt gamma measurements for locating the dose falloff region in the proton therapy [J].

Min, Chul-Hee ;

Kim, Chan Hyeong ;

Youn, Min-Young ;

Kim, Jong-Won .

APPLIED PHYSICS LETTERS, 2006, 89 (18)

[10] Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy [J].

Parodi, Katia ;

Paganetti, Harald ;

Shih, Helen A. ;

Michaud, Susan ;

Loeffler, Jay S. ;

DeLaney, Thomas F. ;

Liebsch, Norbert J. ;

Munzenrider, John E. ;

Fischman, Alan J. ;

Knopf, Antje ;

Bortfeld, Thomas .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 68 (03) :920-934

← 1 2 →