Management of Lung Cancer During the COVID-19 Pandemic

被引:45
作者
Singh, Aditi P. [1 ,2 ]
Berman, Abigail T. [2 ,3 ]
Marmarelis, Melina E. [1 ,2 ]
Haas, Andrew R. [4 ]
Feigenberg, Steven J. [2 ,3 ]
Braun, Jennifer [2 ]
Ciunci, Christine A. [1 ,2 ]
Bauml, Joshua M. [1 ,2 ]
Cohen, Roger B. [1 ,2 ]
Kucharczuk, John C. [5 ]
Shulman, Lawrence N. [1 ,2 ]
Langer, Corey J. [1 ,2 ]
Aggarwal, Charu [1 ,2 ]
机构
[1] Univ Penn, Dept Med, Div Hematol Oncol, Philadelphia, PA 19104 USA
[2] Abramson Canc Ctr, Philadelphia, PA USA
[3] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA
[4] Univ Penn, Dept Med, Div Pulm Allergy & Crit Care, Philadelphia, PA 19104 USA
[5] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
关键词
HYPOFRACTIONATED RADIATION-THERAPY; THORACIC RADIOTHERAPY; CONCURRENT CHEMOTHERAPY; ADJUVANT CHEMOTHERAPY; PHASE-III; CELL; CISPLATIN; ETOPOSIDE; ONCOLOGY; SURVIVAL;
D O I
10.1200/OP.20.00286
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Coronavirus disease 2019 (COVID-19) has had a devastating impact around the world. With high rates of transmission and no curative therapies or vaccine yet available, the current cornerstone of management focuses on prevention by social distancing. This includes decreased health care contact for patients. Patients with lung cancer are a particularly vulnerable population, where the risk of mortality from cancer must now be balanced by the potential risk of a life-threatening infection. In these unprecedented times, a collaborative and multidisciplinary approach is required to streamline but not compromise care. We have developed guidelines at our academic cancer center to standardize management of patients with lung cancer across our health care system and provide guidance to the larger oncology community. We recommend that general principles of lung cancer treatment continue to be followed in most cases where delays could result in rapid cancer progression. We recognize that our recommendations may change over time based on clinical resources and the evolving nature of the COVID-19 pandemic. In principle, however, treatment paradigms must continue to be individualized, with careful consideration of risks and benefits of continuing or altering lung cancer-directed therapy.
引用
收藏
页码:579 / +
页数:10
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