Fabrication of a Bioprinted Composite Kagome Structure Scaffold with Enhanced Mechanical Properties

In bone tissue engineering, to overcome the limitations of traditional bone grafts, biocompatible and biodegradable synthetic polymers and bioceramics are used to fabricate bioprinted scaffolds. However, synthetic polymers have relatively low biocompatibility, and bioceramics are brittle. Therefore, in this study, to enhance the mechanical properties of bioprinted scaffolds for bone regeneration, an ultra-light composite bioprinted scaffold consisting of biodegradable polymer and bioceramic materials with a Kagome structure was proposed. Moreover, the structural characteristics, mechanical properties, and in vitro cell response of the composite Kagome scaffold fabricated using the bioprinting system were assessed and compared with those of a bioprinted scaffold with a grid structure.