Frozen section in thyroid gland follicular neoplasms: It's high time to abandon it!

被引：9

作者：

Sanabria, Alvaro ^{[1
]}

Zafereo, Mark ^{[2
]}

Thompson, Lester D. R. ^{[3
]}

Hernandez-Prera, Juan C. ^{[4
]}

Kowalski, Luiz P. ^{[5
]}

Nixon, Iain J. ^{[6
]}

Shaha, Ashok ^{[7
]}

Rodrigo, Juan P. ^{[8
,9
]}

Makitie, Antti ^{[10
,11
]}

Vander Poorten, Vincent ^{[12
,13
]}

Suarez, Carlos ^{[9
]}

Zbaren, Peter ^{[14
]}

Rinaldo, Alessandra ^{[15
]}

Ferlito, Alfio ^{[16
]}

机构：

[1] Univ Antioquia, Sch Med, Dept Surg, CEXCA,Ctr Excelencia Enfermedades Cabeza & Cuello, Medellin, Colombia

[2] Univ Texas MD Anderson Canc Ctr, Head & Neck Surg, Houston, TX 77030 USA

[3] Woodland Hills Med Ctr, Dept Pathol, Southern Calif Permanente Med Grp, Woodland Hills, CA USA

[4] Moffit Canc Ctr, Dept Pathol, Tampa, FL USA

[5] Univ Sao Paulo, Dept Head & Neck Surg & Otorhinolaryngol, Med Sch, AC Camargo Canc Ctr,Dept Head & Neck Surg, Sao Paulo, SP, Brazil

[6] Univ Edinburgh, NHS Lothian, Ear Nose & Throat Dept, Edinburgh, Midlothian, Scotland

[7] Mem Sloan Kettering Canc Ctr, Head & Neck Serv, 1275 York Ave, New York, NY 10021 USA

[8] Univ Oviedo, Dept Otolaryngol, Hosp Univ Cent Asturias, Oviedo, Spain

[9] CIBERONC, Inst Invest Sanitaria Principado Asturias, IUOPA, Oviedo, Spain

[10] Univ Helsinki, Dept Otorhinolaryngol Head & Neck Surg, Helsinki, Finland

[11] Helsinki Univ Hosp, Helsinki, Finland

[12] Katholieke Univ Leuven, Dept Oncol, Sect Head & Neck Oncol, Leuven, Belgium

[13] Univ Hosp Leuven, Otorhinolaryngol Head & Neck Surg, Leuven, Belgium

[14] Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, Bern, Switzerland

[15] Univ Udine, Sch Med, Udine, Italy

[16] Int Head & Neck Sci Grp, Padua, Italy

来源：

SURGICAL ONCOLOGY-OXFORD | 2021年 / 36卷

关键词：

Thyroid nodule; Frozen section; Follicular neoplasm; Thyroidectomy; Carcinoma; FINE-NEEDLE-ASPIRATION; INTRAOPERATIVE CONSULTATIONS; CYTOLOGY; DIAGNOSIS; CANCER; MANAGEMENT; CARCINOMA; PATHOLOGISTS; NODULES; UTILITY;

D O I：

10.1016/j.suronc.2020.12.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Thyroid nodules are a very common clinical condition. The 2015 American Thyroid Association (ATA) guidelines recommend surgical excision for Bethesda IV nodules. The use of intraoperative frozen section (FS) has been recommended as a strategy to tailor the extent of the initial surgery. We critically evaluated the literature that discusses the utility and cost-effectiveness of FS to make an intraoperative decision in patients with thyroid nodules classified as follicular neoplasm. FS should not be recommended as a routine intraoperative test to assess for malignancy in thyroid follicular patterned lesions due to its low performance; the high number of deferred results; the inability to adequately assess histologically defining features; the improvements in risk stratification guiding total thyroidectomy; and the low cost-effectiveness of FS.

引用

页码：76 / 81

页数：6

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