The Irish living kidney donor program - why potential donors do not proceed to live kidney donation?

被引：20

作者：

Connaughton, Dervla M. ^{[1
]}

Harmon, Grainne ^{[2
]}

Cooney, Anne ^{[1
]}

Williams, Yvonne ^{[1
]}

O'Regan, John ^{[1
]}

O'Neill, Derek ^{[2
]}

Cunningham, Phyllis ^{[3
]}

Counihan, Aileen ^{[3
]}

O'Kelly, Patrick ^{[1
]}

McHale, Siobhan ^{[4
]}

Denton, Mark ^{[1
]}

O'Seaghdha, Conall M. ^{[1
]}

Magee, Colm ^{[1
]}

Conlon, Peter ^{[1
]}

Little, Dilly ^{[5
]}

Keogan, Mary ^{[2
]}

de Freitas, Declan G. ^{[1
]}

机构：

[1] Beaumont Hosp, Dept Nephrol & Transplantat, Dublin 9, Ireland

[2] Beaumont Hosp, Natl Histocompatibil & Immunogenet Serv Solid Org, Dublin 9, Ireland

[3] Beaumont Hosp, Dept Kidney Transplantat & Urol, Transplant Coordinator Serv, Dublin 9, Ireland

[4] Beaumont Hosp, Dept Psychiat, Dublin 9, Ireland

[5] Beaumont Hosp, Dept Kidney Transplantat & Urol, Dublin 9, Ireland

来源：

CLINICAL TRANSPLANTATION | 2016年 / 30卷 / 01期

关键词：

donor assessment; kidney transplantation; living donors; renal transplant; transplant immunology; RENAL-TRANSPLANTATION; EXPERIENCE; RISK;

D O I：

10.1111/ctr.12641

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BackgroundLiving donation is not only a method to increase access to kidney transplantation but can also offer superior outcomes. We report the experience of the living donor (LD) program in the Republic of Ireland and explore reasons why potential donors do not proceed to live donation. MethodsRetrospective cohort study of all potential donors from January 2000 to March 2014 who presented wishing to undergo donor work-up and their subsequent outcomes. ResultsA total of 956 donors for 496 recipients contacted the live kidney donation program of which 883 potential donors proceeded to the initial stage of assessment. The donor dropout rate at this stage was 64.2% (614/956 potential donors did not proceed to further evaluation). Thereafter, 269 (28.1%) donors underwent further assessment by the multidisciplinary team. In total, 93 (9.7%) donors were declined following this assessment with 176 (18.4%) donors ultimately proceeding to live kidney donation. The major reason for declining a donor was a medical contraindication (n = 63, 67.7%). In term of recipients, 54.2% (n = 269/496) had a potential donor proceed for further assessment of which 65.4% (n = 176/269) ultimately proceeding to live donation. ConclusionFurther evaluation of the declined donor group is warranted to allow for expansion of the LD program.

引用

页码：17 / 25

页数：9

共 19 条

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