A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration

被引：13

作者：

Hara, Satoshi ^{[1
,2
]}

Kawano, Mitsuhiro ^{[1
]}

Mizushima, Ichiro ^{[1
]}

Yamada, Kazunori ^{[1
]}

Fujita, Kentaro ^{[3
]}

Harada, Kenichi ^{[4
]}

Matsumura, Masami ^{[5
]}

Yamagishi, Masakazu ^{[6
]}

Sato, Yasuharu ^{[7
]}

Yamaguchi, Yutaka ^{[8
]}

Nakanuma, Yasuni ^{[4
]}

Nagata, Michio ^{[2
]}

机构：

[1] Kanazawa Univ, Grad Sch Med, Dept Internal Med, Div Rheumatol, Kanazawa, Ishikawa, Japan

[2] Univ Tsukuba, Grad Sch Comprehens Human Sci, Dept Kidney & Vasc Pathol, 1-1-1Tennoudai, Tsukuba, Ibaraki, Japan

[3] Kanazawa Univ, Grad Sch Med, Dept Resp Med, Kanazawa, Ishikawa, Japan

[4] Kanazawa Univ, Grad Sch Med, Dept Human Pathol, Kanazawa, Ishikawa, Japan

[5] Jichi Med Univ, Sch Med, Ctr Community Med, Div Gen Med, Shimotsuke, Tochigi, Japan

[6] Kanazawa Univ, Grad Sch Med, Dept Internal Med, Div Cardiol, Kanazawa, Ishikawa, Japan

[7] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol, Okayama, Japan

[8] Yamaguchis Pathol Lab, Chiba, Japan

来源：

MODERN RHEUMATOLOGY | 2016年 / 26卷 / 05期

关键词：

IgG4-related disease; IgG4; Tubulointerstitial nephritis; REGULATORY IMMUNE-REACTIONS; TUBULOINTERSTITIAL NEPHRITIS; SCLEROSING PANCREATITIS; DIAGNOSTIC-CRITERIA; KIDNEY-DISEASE; PATHOLOGY; TH2;

D O I：

10.3109/14397595.2014.916836

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a 74-year-old Japanese man with systemic fibroinflammatory conditions closely resembling those of immunoglobulin G4-related disease (IgG4-RD). Radiology and histology showed characteristics of IgG4-related tubulointerstitial nephritis, despite normal serum IgG4 value and scanty IgG4-positive plasma cell infiltration in each organ. This case suggests that a condition closely mimicking IgG4-RD may develop without IgG4-positive plasma cells and those exceptional cases should also be taken into account in the differential diagnosis of IgG4-RD.

引用

页码：784 / 789

页数：6

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