Lens intermediate filaments

被引：41
作者：
FitzGerald, Paul G. [1 ]
机构：
[1] Univ Calif Davis, Dept Cell Biol & Human Anat, Sch Med, Davis, CA 95616 USA
来源：
EXPERIMENTAL EYE RESEARCH | 2009年 / 88卷 / 02期
基金：
美国国家卫生研究院;
关键词：
lens; Intermediate filaments; beaded filaments; vimentin; filensin; CP49; Phakinin; Phakosin; FIBER CELL-DIFFERENTIATION; FIBRILLARY ACIDIC PROTEIN; ALPHA-B-CRYSTALLIN; DOMINANT CONGENITAL CATARACT; MEESMANNS CORNEAL-DYSTROPHY; EXTRINSIC MEMBRANE-PROTEIN; HUMAN CP49 GENE; BEADED-FILAMENT; CYTOSKELETAL PROTEIN; BOVINE LENS;
D O I：
10.1016/j.exer.2008.11.007
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates. Some of the key features of both filament systems are reviewed. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：165 / 172
页数：8
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