Quality Improvement Program Increases Early Tracheal Extubation Rate and Decreases Pulmonary Complications and Resource Utilization After Cardiac Surgery

被引:49
作者
Camp, Sara L. [1 ]
Stamou, Sotiris C. [1 ]
Stiegel, Robert M. [1 ]
Reames, Mark K. [1 ]
Skipper, Eric R. [1 ]
Madjarov, Jeko [1 ]
Velardo, Bernard [2 ]
Geller, Harley [2 ]
Nussbaum, Marcy [1 ]
Geller, Rachel [1 ]
Robicsek, Francis [1 ]
Lobdell, Kevin W. [1 ]
机构
[1] Carolinas Heart & Vasc Inst, Dept Thorac & Cardiovasc Surg, Charlotte, NC 28203 USA
[2] Carolinas Heart & Vasc Inst, Dept Anesthesiol, Charlotte, NC 28203 USA
关键词
VENTILATOR-ASSOCIATED PNEUMONIA; HEART-SURGERY; CONTROLLED-TRIAL; BYPASS-SURGERY; ORAL RINSE; CARE; PREVALENCE; MORTALITY; INFECTION;
D O I
10.1111/j.1540-8191.2008.00783.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
P>Background: Early tracheal extubation is a common goal after cardiac surgery and may improve postoperative outcomes. Our study evaluates the impact of a quality improvement program (QIP) on early extubation, pulmonary complications, and resource utilization after cardiac surgery. Methods: Between 2002 and 2006, 980 patients underwent early tracheal extubation (< 6 hours after surgery) and 1231 had conventional extubation (> 6 hours after surgery, conventional group). Outcomes compared between the two groups included: (1) pneumonia, (2) sepsis, (3) intensive care unit (ICU) length of stay, (4) hospital length of stay, (5) ICU readmission, and (6) reintubation. Logistic regression analysis and propensity score adjustment were used to adjust for imbalances in the patients' preoperative characteristics. Results: Early extubation rates were significantly increased with QIP (QIP 53% vs. Non-QIP 38%, p = 0.01). Early extubation was associated with a lower rate of (1) pneumonia (odds ratio [OR] = 0.35, 95% confidence intervals [CI] = 0.22-0.55, p < 0.001), (2) sepsis (OR = 0.38, CI = 0.20-0.74, p < 0.004), (3) prolonged ICU length of stay (OR = 0.42, CI = 0.35-0.50, p < 0.001), (4) hospital length of stay (OR = 0.37, CI = 0.29-0.47, p < 0.001), (5) ICU readmission (OR = 0.55, CI = 0.39-0.78, p < 0.001), and (6) reintubation (OR = 0.53, CI = 0.34-0.81, p < 0.003) both in multivariable logistic regression analysis and propensity score adjustment. Conclusions: QIP and early tracheal extubation reduce pulmonary complications and resource utilization after cardiac surgery. (J Card Surg 2009;24:414-423).
引用
收藏
页码:414 / 423
页数:10
相关论文
共 26 条
[1]  
Bouza E, 2003, CRIT CARE MED, V31, P1964, DOI [10.1097/01.ccm.0000084807.15352.93, 10.1097/01.CCM.0000084807.15352.93]
[2]   Randomized assessment of resource use in fast-track cardiac surgery 1-year after hospital discharge [J].
Cheng, DCH ;
Wall, C ;
Djaiani, G ;
Peragallo, RA ;
Carroll, J ;
Li, C ;
Naylor, D .
ANESTHESIOLOGY, 2003, 98 (03) :651-657
[3]   Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: A prospective randomized controlled trial [J].
Cheng, DCH ;
Karski, J ;
Peniston, C ;
Asokumar, B ;
Raveendran, G ;
Carroll, J ;
Nierenberg, H ;
Roger, S ;
Mickle, D ;
Tong, J ;
Zelovitsky, J ;
David, T ;
Sandler, A .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1996, 112 (03) :755-764
[4]  
D'Agostino RB, 1998, STAT MED, V17, P2265, DOI 10.1002/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO
[5]  
2-B
[6]   Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery [J].
DeRiso, A ;
Ladowski, JS ;
Dillon, TA ;
Justice, JW ;
Peterson, AC .
CHEST, 1996, 109 (06) :1556-1561
[7]  
GALL SA, 1988, J THORAC CARDIOV SUR, V95, P819
[8]   Outcomes of early extubation after bypass surgery in the elderly [J].
Guller, U ;
Anstrom, KJ ;
Holman, WL ;
Allman, RM ;
Sansom, M ;
Peterson, ED .
ANNALS OF THORACIC SURGERY, 2004, 77 (03) :781-788
[9]  
Hammon J W., 2008, Cardiac Surgery in the Adult, P389
[10]  
HAWKES CA, 2007, COCHRANE DB SYST REV