Teratogenic effects of N-ethyl-N-nitrosourea (ENU) on larvae of the self-fertilizing fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae)

被引：5

作者：

Lee, JS ^{[1
]}

Chang, SY

Kim, IC

Han, MS

Lee, YS

机构：

[1] Hanyang Univ, Grad Sch, Dept Environm Sci, Seoul, South Korea

[2] Hanyang Univ, Coll Med, Clin Invest Lab, Seoul, South Korea

[3] Hanyang Univ, Coll Nat Sci, Dept Life Sci, Seoul, South Korea

[4] Hanyang Univ, Coll Sci, Dept Biochem & Mol Biol, Ansan 425781, South Korea

来源：

TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS | 2002年 / 22卷 / 05期

关键词：

Rivulus marmoratus; N-ethyl-N-nitrosourea; larvae; fish; teratogenesis;

D O I：

10.1002/tcm.10031

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We showed that N-Ethyl-N-Nitrosourea (ENU) induces teratogenesis in larvae of the self-fertilizing fish Rivulus marmoratus. We discuss this and the issue of carcinogenesis caused by ENU. (C) 2002 Wiley-Liss, Inc.

引用

页码：363 / 367

页数：5

共 27 条

[1] TERRESTRIALITY IN THE CYPRINODONTID FISH RIVULUS-MARMORATUS - POTENTIAL UTILITY IN H2S AND OTHER BIOASSAYS [J].

ABEL, DC .

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1984, 33 (01) :33-39

[2] Ethylnitrosourea induces neoplasia in zebrafish (Danio rerio) [J].

Beckwith, LG ;

Moore, JL ;

Tsao-Wu, GS ;

Harshbarger, JC ;

Cheng, KC .

LABORATORY INVESTIGATION, 2000, 80 (03) :379-385

[3]

COUCH JA, 1995, CANCER RES, V55, P2438

[4] Genome-wide, large-scale production of mutant mice by ENU mutagenesis [J].

de Angelis, MH ;

Flaswinkel, H ;

Fuchs, H ;

Rathkolb, B ;

Soewarto, D ;

Marschall, S ;

Heffner, S ;

Pargent, W ;

Wuensch, K ;

Jung, M ;

Reis, A ;

Richter, T ;

Alessandrini, F ;

Jakob, T ;

Fuchs, E ;

Kolb, H ;

Kremmer, E ;

Schaeble, K ;

Rollinski, B ;

Roscher, A ;

Peters, C ;

Meitinger, T ;

Strom, T ;

Steckler, T ;

Holsboer, F ;

Klopstock, T ;

Gekeler, F ;

Schindewolf, C ;

Jung, T ;

Avraham, K ;

Behrendt, H ;

Ring, J ;

Zimmer, A ;

Schughart, K ;

Pfeffer, K ;

Wolf, E ;

Balling, R .

NATURE GENETICS, 2000, 25 (04) :444-447

[5]

DREOSTI IE, 1983, RES COMMUN CHEM PATH, V41, P265

[6]

FOX RR, 1980, J NATL CANCER I, V65, P607

[7] N-ALKYL-N-NITROSOUREA INDUCED SECONDARY STRUCTURAL-CHANGES IN DNA FROM RAT EMBRYOS AND FETAL BRAINS INVIVO [J].

HUANG, PHT ;

CATALANO, A .

TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 1992, 12 (03) :135-153

[8]

Imai Y, 2000, GENETICS, V155, P261

[9]

Ivankovic S, 1979, Natl Cancer Inst Monogr, P103

[10]

Lee JS, 2000, TERATOGEN CARCIN MUT, V20, P1, DOI 10.1002/(SICI)1520-6866(2000)20:1<1::AID-TCM1>3.0.CO

← 1 2 3 →