Bisbenzylisoquinoline alkaloids from Stephania cepharantha and their effects on proliferation of cultured cells from the murine hair apparatus

被引：22

作者：

Nakaoji, K ^{[1
]}

Nayeshiro, H ^{[1
]}

Tanahashi, T ^{[1
]}

Su, Y ^{[1
]}

Nagakura, N ^{[1
]}

机构：

[1] KOBE PHARMACEUT UNIV,HIGASHINADA KU,KOBE,HYOGO 658,JAPAN

来源：

PLANTA MEDICA | 1997年 / 63卷 / 05期

关键词：

Hair cells; proliferation; Stephania cepharantha; Menispermaceae; bisbenzylisoquinoline alkaloids; cepharanthine;

D O I：

10.1055/s-2006-957726

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bisbenzylisoquinoline alkaloids were isolated from Stephania cepharantha Hayata and their proliferative activities on cultured hair cells from the murine skin were evaluated. Cepharanthine (1), cepharanoline (9), isotetrandrine (2), and berbamine (7) showed significant activities in the range of 0.01 - 0.1 mu g/ml, but had no activity on cultured keratinocytes or fibroblasts from the murine skin.

引用

页码：425 / 428

页数：4

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