Versatility of Hydrogels: From Synthetic Strategies, Classification, and Properties to Biomedical Applications

被引：195

作者：

Ahmad, Zubair ^{[1
]}

Salman, Saad ^{[2
]}

Khan, Shahid Ali ^{[3
]}

Amin, Abdul ^{[1
]}

Rahman, Zia Ur ^{[1
]}

Al-Ghamdi, Youssef O. ^{[4
]}

Akhtar, Kalsoom ^{[5
]}

Bakhsh, Esraa M. ^{[5
]}

Khan, Sher Bahadar ^{[5
,6
]}

机构：

[1] Univ Swabi, Dept Chem, Swabi 23561, Pakistan

[2] Capital Univ Sci & Technol, Fac Pharm, Islamabad 44000, Pakistan

[3] Natl Univ Sci & Technol, Sch Nat Sci, Dept Chem, Islamabad 44000, Pakistan

[4] Majmaah Univ, Coll Sci Al Zulfi, Dept Chem, Al Majmaah 11952, Saudi Arabia

[5] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia

[6] King Abdulaziz Univ, Ctr Excellence Adv Mat Res, Jeddah 21589, Saudi Arabia

来源：

GELS | 2022年 / 8卷 / 03期

关键词：

hydrogels; synthetic strategies; classification; applications; wound healing; drug delivery; CROSS-LINKED HYDROGELS; MECHANICAL-PROPERTIES; SENSITIVE HYDROGELS; DRUG-DELIVERY; RHEOLOGICAL CHARACTERIZATION; BIODEGRADABLE HYDROGELS; CHITOSAN HYDROGELS; ALGINATE HYDROGELS; GAMMA-IRRADIATION; POLYMERIC CARRIER;

D O I：

10.3390/gels8030167

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Hydrogels are three-dimensional, cross-linked, and supramolecular networks that can absorb significant volumes of water. Hydrogels are one of the most promising biomaterials in the biological and biomedical fields, thanks to their hydrophilic properties, biocompatibility, and wide therapeutic potential. Owing to their nontoxic nature and safe use, they are widely accepted for various biomedical applications such as wound dressing, controlled drug delivery, bone regeneration, tissue engineering, biosensors, and artificial contact lenses. Herein, this review comprises different synthetic strategies for hydrogels and their chemical/physical characteristics, and various analytical, optical, and spectroscopic tools for their characterization are discussed. A range of synthetic approaches is also covered for the synthesis and design of hydrogels. It will also cover biomedical applications such as bone regeneration, tissue engineering, and drug delivery. This review addressed the fundamental, general, and applied features of hydrogels in order to facilitate undergraduates, graduates, biomedical students, and researchers in a variety of domains.

引用

页数：25

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