Severe osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus

被引：19

作者：

Moumile, Kaoutar

Cadilhac, Celine

Lina, Gerard

Berche, Patrick

Glorion, Christophe

Ferroni, Agnes ^{[1
]}

机构：

[1] Hop Necker Enfants Malad, AP HP, Microbiol Lab, F-75015 Paris, France

[2] Hop Necker Enfants Malad, AP HP, Serv Chirurg Orthoped Pediat, F-75015 Paris, France

[3] Hop Edouard Herriot, Ctr Natl Reference Staphylocoques, F-69003 Lyon, France

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2006年 / 56卷 / 01期

关键词：

Panton-Valentine leukocidin; Staphylococcus aureus; osteoarticular infection;

D O I：

10.1016/j.diagmicrobio.2006.03.007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report here a case of osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus. The 3-year-old child presented osteoarthritis associated with toxic shock syndrome, which was complicated by thrombosis, pneumonia, and diaphysitis, despite appropriate antibiotic treatment. Osteitis associated with toxinogenic S. aureus is rarely described. This case highlights the need of early and aggressive surgical treatment, in addition to appropriate antimicrobial therapy. (c) 2006 Elsevier Inc. All rights reserved.

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页码：95 / 97

页数：3

相关论文

共 10 条

[1] Staphylococcal and streptococcal superantigens:: molecular, biological and clinical aspects [J].

Alouf, JE ;

Müller-Alouf, H .

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2003, 292 (7-8) :429-440

[2] Neutralization of Staphylococcus aureus Panton Valentine leukocidin by intravenous immunoglobulin in vitro [J].

Gauduchon, V ;

Cozon, G ;

Vandenesch, F ;

Genestier, AL ;

Eyssade, N ;

Peyrol, S ;

Etienne, J ;

Lina, G .

JOURNAL OF INFECTIOUS DISEASES, 2004, 189 (02) :346-353

[3] Staphylococcus aureus isolates carrying panton-valentine leucocidin genes in England and Wales:: Frequency, characterization, and association with clinical disease [J].

Holmes, A ;

Ganner, M ;

McGuane, S ;

Pitt, TL ;

Cookson, BD ;

Kearns, AM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (05) :2384-2390

[4] EFFECTS OF STAPHYLOCOCCUS-AUREUS LEUKOCIDINS ON INFLAMMATORY MEDIATOR RELEASE FROM HUMAN GRANULOCYTES [J].

KONIG, B ;

PREVOST, G ;

PIEMONT, Y ;

KONIG, W .

JOURNAL OF INFECTIOUS DISEASES, 1995, 171 (03) :607-613

[5] Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia [J].

Lina, G ;

Piémont, Y ;

Godail-Gamot, F ;

Bes, M ;

Peter, MO ;

Gauduchon, V ;

Vandenesch, F ;

Etienne, J .

CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1128-1132

[6]

Marie-Cardine A, 2001, ARCH PEDIATR, V8, P792

[7] Toxic shock syndrome and bacterial superantigens: An update [J].

McCormick, JK ;

Yarwood, JM ;

Schlievert, PM .

ANNUAL REVIEW OF MICROBIOLOGY, 2001, 55 :77-104

[8] Epidemiology of antibiotic susceptibility and leucotoxin production by Staphylococcus aureus isolates in West Africa. [J].

Moussa, LB ;

Sanni, A ;

Dagnra, AY ;

Anagonou, S ;

Prince-David, M ;

Edoh, V ;

Befort, JJ ;

Prévost, G ;

Monteil, H .

MEDECINE ET MALADIES INFECTIEUSES, 1999, 29 (11) :689-696

[9]

NORBYTEGLUND A, 1996, INFECT IMMUN, V64, P5395

[10] EPIDEMIOLOGIC DATA ON STAPHYLOCOCCUS-AUREUS STRAINS PRODUCING SYNERGOHYMENOTROPIC TOXINS [J].

PREVOST, G ;

COUPPIE, P ;

PREVOST, P ;

GAYET, S ;

PETIAU, P ;

CRIBIER, B ;

MONTEIL, H ;

PIEMONT, Y .

JOURNAL OF MEDICAL MICROBIOLOGY, 1995, 42 (04) :237-245