Balancing Covariates via Propensity Score Weighting

被引:627
作者
Li, Fan [1 ]
Morgan, Kari Lock [2 ]
Zaslavsky, Alan M. [3 ]
机构
[1] Duke Univ, Dept Stat Sci, Durham, NC 27705 USA
[2] Penn State Univ, Dept Stat, University Pk, PA 16802 USA
[3] Harvard Med Sch, Dept Hlth Care Policy, Boston, MA USA
关键词
Balancing weights; Causal inference; Clinical equipoise; Confounding; Exact balance; Overlap weights; CAUSAL INFERENCE; MODELS; OVERLAP; CARE;
D O I
10.1080/01621459.2016.1260466
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Covariate balance is crucial for unconfounded descriptive or causal comparisons. However, lack of balance is common in observational studies. This article considers weighting strategies for balancing covariates. We define a general class of weightsthe balancing weightsthat balance the weighted distributions of the covariates between treatment groups. These weights incorporate the propensity score to weight each group to an analyst-selected target population. This class unifies existing weighting methods, including commonly used weights such as inverse-probability weights as special cases. General large-sample results on nonparametric estimation based on these weights are derived. We further propose a new weighting scheme, the overlap weights, in which each unit's weight is proportional to the probability of that unit being assigned to the opposite group. The overlap weights are bounded, and minimize the asymptotic variance of the weighted average treatment effect among the class of balancing weights. The overlap weights also possess a desirable small-sample exact balance property, based on which we propose a new method that achieves exact balance for means of any selected set of covariates. Two applications illustrate these methods and compare them with other approaches.
引用
收藏
页码:390 / 400
页数:11
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