Synthetic studies of benzo[b]pyrrolo[4,3,2-de][1,10]phenanthroline

被引：31

作者：

Kitahara, Y ^{[1
]}

Mizuno, T ^{[1
]}

Kubo, A ^{[1
]}

机构：

[1] Meiji Pharmaceut Univ, Tokyo 2048588, Japan

来源：

TETRAHEDRON | 2004年 / 60卷 / 19期

关键词：

acridine; phenanthroline; nitration; cyclization;

D O I：

10.1016/j.tet.2004.03.057

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

6,11-Dihydrobenzo[b]pyrrolo[4,3,2-de][1,10]phenanthroline-5,8-dione (6), which possesses a unique heterocyclic ring system similar to that in plakinidines A-D (1-4), was synthesized from 2-acetyl-3'-nitrodiphenylamine (16) in nine steps. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：4283 / 4288

页数：6

相关论文

共 8 条

[1] SYNTHESIS OF SOME PYRROLO[4,3,2-DE]QUINOLINES [J].

BALCZEWSKI, P ;

JOULE, JA ;

ESTEVEZ, C ;

ALVAREZ, M .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (16) :4571-4575

[2] SYNTHESIS OF 4(1H)-QUINOLONES BY THERMOLYSIS OF ARYLAMINOMETHYLENE MELDRUM ACID-DERIVATIVES [J].

CASSIS, R ;

TAPIA, R ;

VALDERRAMA, JA .

SYNTHETIC COMMUNICATIONS, 1985, 15 (02) :125-133

[3] NOVEL MARINE SPONGE ALKALOIDS .1. PLAKINIDINE-A AND PLAKINIDINE-B, ANTHELMINTIC ACTIVE ALKALOIDS FROM A PLAKORTIS SPONGE [J].

INMAN, WD ;

ONEILLJOHNSON, M ;

CREWS, P .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (01) :1-4

[4] TOTAL SYNTHESIS OF EUPOLAURAMINE [J].

KAWASE, M ;

MIYAKE, Y ;

SAKAMOTO, T ;

SHIMADA, M ;

KIKUGAWA, Y .

TETRAHEDRON, 1989, 45 (06) :1653-1660

[5]

KEMPTER G, 1971, Z CHEM, V11, P104

[6]

KEMPTER G, 1971, Patent No. 84386

[7]

LEDOCHOWSKI A, 1977, ROCZ CHEM, V51, P2013

[8] Plakinidine D, a new pyrroloacridine alkaloid from two ascidians of the genus Didemnum [J].

Smith, CJ ;

Venables, DA ;

Hopmann, C ;

Salomon, CE ;

Jompa, J ;

Tahir, A ;

Faulkner, DJ ;

Ireland, CM .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (10) :1048-1050