Standardizing care for acute decompensated heart failure in a large megatrial: The approach for the Acute Studies of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure (ASCEND-HF)

被引：27

作者：

Ezekowitz, Justin A. ^{[1
]}

Hernandez, Adrian F. ^{[2
]}

Starling, Randall C. ^{[3
]}

Yancy, Clyde W. ^{[4
]}

Massie, Barry ^{[5
]}

Hill, James A. ^{[6
]}

Krum, Henry ^{[7
]}

Diaz, Rafael ^{[8
]}

Ponikowski, Piotr ^{[9
]}

Metra, Marco ^{[10
]}

Howlett, Jonathon G. ^{[11
]}

Gennevois, Daniel ^{[12
]}

O'Connor, Christopher M. ^{[2
]}

Califf, Robert M. ^{[2
]}

Fonarow, Gregg C. ^{[13
]}

机构：

[1] Univ Alberta, Cardiol WMC 2C2, Div Cardiol, Edmonton, AB T6G 2B7, Canada

[2] Duke Univ, Med Ctr, Duke Clin Res Inst, Durham, NC USA

[3] Cleveland Clin Fdn, Dept Cardiovasc Med, Kaufman Ctr Heart Failure, Lerner Coll Med, Cleveland, OH 44195 USA

[4] Baylor Heart & Vasc Inst, Dallas, TX USA

[5] Univ Calif San Francisco, San Francisco VA Hosp, San Francisco, CA 94143 USA

[6] Univ Florida, Coll Med, Div Cardiovasc Med, Gainesville, FL USA

[7] Monash Univ, Alfred Hosp, Melbourne, Vic 3181, Australia

[8] Inst Cardiovasc Rosario, Rosario, Santa Fe, Argentina

[9] Mil Hosp, Dept Cardiol, Wroclaw, Poland

[10] Univ Brescia, Dept Expt & Appl Med, Sect Cardiovasc Dis, Brescia, Italy

[11] Dalhousie Univ, Div Cardiol, Halifax, NS, Canada

[12] Johnson & Johnson Inc, Mountain View, CA USA

[13] Univ Calif Los Angeles, David Geffen Sch Med, Div Cardiol, Los Angeles, CA 90095 USA

来源：

AMERICAN HEART JOURNAL | 2009年 / 157卷 / 02期

基金：

加拿大健康研究院;

关键词：

QUALITY-OF-CARE; SURVEY PROGRAM; GUIDELINES; OUTCOMES; MORTALITY; DIAGNOSIS; MANAGEMENT; UPDATE; VENTILATION; PREVENTION;

D O I：

10.1016/j.ahj.2008.10.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute decompensated heart failure (ADHF) is a major public health issue and remains a heterogeneous, complex, and difficult condition to manage. Although novel acute therapies are being tested in large randomized clinical trials, opportunities exist to improve the standard of care by ensuring optimal adherence to currently established evidence-based interventions for HF. Consideration of the goals of therapy and practical application of current methods to assess for clinical improvement may lead to improved patient management and possibly improved outcomes for patients with ADHF. This review provides key practical information regarding the current standard of care for patients with ADHF including the goals of therapy, management of acute and chronic medications, and discharge/transition of care planning. (Am Heart J 2009; 157:219-28.)

引用

页码：219 / 228

页数：10

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