Anti-inflammatory activity of methanolic extract of Eclipta prostrata L. (Astearaceae)

被引：0

作者：

Arunachalam, G. ^{[1
]}

Subramanian, N. ^{[2
]}

Pazhani, G. P. ^{[3
]}

Ravichandran, V. ^{[4
]}

机构：

[1] Pharmaceut Sci Res Inst, PGP Coll, Namakkal 637207, Tamil Nadu, India

[2] Anna Univ, Bharathidasan Inst Technol, Tiruchirappalli 620024, Tamil Nadu, India

[3] KRS Pallavan Coll Pharm, Mannur 602105, Tamil Nadu, India

[4] Vels Coll Pharm, Madras 600035, Tamil Nadu, India

来源：

AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY | 2009年 / 3卷 / 03期

关键词：

Eclipta prostrate; methanolic extract; albino Wistar rats; anti-inflammatory activity; PLANTS; EDEMA; VENOM; RAT; PAW;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The methanolic extract of leaves of Eclipta prostrata Linn was investigated for anti-inflammatory activity in albino Wistar rats. The methanolic extract administered by the oral route at a concentration of 100 and 200 mg kg(-1) showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug indomethacin (10 mg kg(-1)) and cyproheptadine (8 mg kg(-1)). The results lend support to the traditional use of E. prostrata in the treatment of inflammatory diseases.

引用

页码：97 / 100

页数：4

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