Historical Perspective and Future Direction of Blood Vessel Developments

被引：44

作者：

Dimitrievska, Sashka ^{[1
,2
]}

Niklason, Laura E. ^{[2
,3
]}

机构：

[1] Howard Hughes Med Inst, Chevy Chase, MD 20815 USA

[2] Yale Univ, Dept Biomed Engn, New Haven, CT 06520 USA

[3] Yale Univ, Dept Anesthesiol, New Haven, CT 06520 USA

来源：

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE | 2018年 / 8卷 / 02期

关键词：

ENGINEERED VASCULAR GRAFT; SAPHENOUS-VEIN; CELLS; SCAFFOLDS; ENDOTHELIALIZATION; MEMBRANE; IMPROVES; PROPERTY; ARTERIES; COLLAGEN;

D O I：

10.1101/cshperspect.a025742

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Over the past 40 years, remarkable advances have been made in our understanding of successful blood vessel regeneration, starting with the failures of early tissue-engineered vascular grafts designed using isolated components or molecules, such as collagen gels. The vascular tissue engineers are today better educated and have steered ongoing research developments toward clinical developments of more complete vascular grafts that replicate the multitude of specialized arterial aspects required for function.

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