Microarray technology - enhanced versatility, persistent challenge

被引：96

作者：

Epstein, CB ^{[1
]}

Butow, RA ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2000年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0958-1669(99)00065-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microarray analysis of nucleic acid related phenomena on a genome-wide scale is now a proven technology New applications of the method are appearing rapidly and problems unique to the handling and interpretation of the large data sets produced by the technique are beginning to be addressed.

引用

页码：36 / 41

页数：6

共 50 条

[1] Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays [J].

Alon, U ;

Barkai, N ;

Notterman, DA ;

Gish, K ;

Ybarra, S ;

Mack, D ;

Levine, AJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (12) :6745-6750

[2] Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses [J].

Amundson, SA ;

Bittner, M ;

Chen, YD ;

Trent, J ;

Meltzer, P ;

Fornace, AJ .

ONCOGENE, 1999, 18 (24) :3666-3672

[3] Gene expression informatics - it's all in your mine [J].

Bassett, DE ;

Eisen, MB ;

Boguski, MS .

NATURE GENETICS, 1999, 21 (Suppl 1) :51-55

[4] Comparative genomics of BCG vaccines by whole-genome DNA microarray [J].

Behr, MA ;

Wilson, MA ;

Gill, WP ;

Salamon, H ;

Schoolnik, GK ;

Rane, S ;

Small, PM .

SCIENCE, 1999, 284 (5419) :1520-1523

[5] Options available - from start to finish - for obtaining expression data by microarray [J].

Bowtell, DDL .

NATURE GENETICS, 1999, 21 (Suppl 1) :25-32

[6] The integration of microarray information in the drug development process [J].

Braxton, S ;

Bedilion, T .

CURRENT OPINION IN BIOTECHNOLOGY, 1998, 9 (06) :643-649

[7] Characterization of differentially expressed genes in purified Drosophila follicle cells:: Toward a general strategy for cell type-specific developmental analysis [J].

Bryant, Z ;

Subrahmanyan, L ;

Tworoger, M ;

LaTray, L ;

Liu, CR ;

Li, MJ ;

van den Engh, G ;

Ruohola-Baker, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (10) :5559-5564

[8] Characterization of single-nucleotide polymorphisms in coding regions of human genes [J].

Cargill, M ;

Altshuler, D ;

Ireland, J ;

Sklar, P ;

Ardlie, K ;

Patil, N ;

Lane, CR ;

Lim, EP ;

Kalyanaraman, N ;

Nemesh, J ;

Ziaugra, L ;

Friedland, L ;

Rolfe, A ;

Warrington, J ;

Lipshutz, R ;

Daley, GQ ;

Lander, ES .

NATURE GENETICS, 1999, 22 (03) :231-238

[9]

Chen Y, 1997, J Biomed Opt, V2, P364, DOI 10.1117/12.281504

[10] A genome-wide transcriptional analysis of the mitotic cell cycle [J].

Cho, RJ ;

Campbell, MJ ;

Winzeler, EA ;

Steinmetz, L ;

Conway, A ;

Wodicka, L ;

Wolfsberg, TG ;

Gabrielian, AE ;

Landsman, D ;

Lockhart, DJ ;

Davis, RW .

MOLECULAR CELL, 1998, 2 (01) :65-73

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