Large Heterogeneity Observed in Single Molecule Measurements of Intramolecular Electron Transfer Rates through DNA

被引：4

作者：

Fan, Shuya

Takada, Tadao ^{[1
,2
]}

Maruyama, Atsushi ^{[3
]}

Fujitsuka, Mamoru ^{[1
]}

Kawai, Kiyohiko ^{[1
]}

机构：

[1] Osaka Univ, SANKEN Inst Sci & Ind Res, 8-1 Mihogaoka, Ibaraki, Osaka 5670047, Japan

[2] Univ Hyogo, Grad Sch Engn, Dept Appl Chem, 2167 Shosha, Himeji, Hyogo 6712280, Japan

[3] Tokyo Inst Technol, Dept Life Sci & Technol, 4259 B-57 Nagatsuta,Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2022年 / 95卷 / 12期

关键词：

Electron transfer; Single molecule measurement; Blinking; LONG-RANGE ELECTRON; CHARGE-TRANSFER; HOLE-TRANSFER; DISTANCE; DYNAMICS; FLUORESCENCE; KINETICS; ENERGY; BASES;

D O I：

10.1246/bcsj.20220220

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Current understanding of electron transfer (ET) kinetics is largely based on ensemble measurements that obscure the underlying single-molecule behavior. We previously reported systematic distance-dependent single molecule ET measure-ments that show a large heterogeneity. Here we study and dis-cuss this heterogeneity in more detail and suggest that it is a rather fundamental phenomenon that is difficult to explain solely by the distribution of DNA conformations. This hetero-geneity may arise from the uniqueness of each molecule, or it may reflect the uncertainty of ET kinetics.

引用

收藏

页码：1697 / 1702

页数：6

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