Large Heterogeneity Observed in Single Molecule Measurements of Intramolecular Electron Transfer Rates through DNA

被引：3
作者：
Fan, Shuya
Takada, Tadao [1 ,2 ]
Maruyama, Atsushi [3 ]
Fujitsuka, Mamoru [1 ]
Kawai, Kiyohiko [1 ]
机构：
[1] Osaka Univ, SANKEN Inst Sci & Ind Res, 8-1 Mihogaoka, Ibaraki, Osaka 5670047, Japan
[2] Univ Hyogo, Grad Sch Engn, Dept Appl Chem, 2167 Shosha, Himeji, Hyogo 6712280, Japan
[3] Tokyo Inst Technol, Dept Life Sci & Technol, 4259 B-57 Nagatsuta,Midori Ku, Yokohama, Kanagawa 2268501, Japan
来源：
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2022年 / 95卷 / 12期
关键词：
Electron transfer; Single molecule measurement; Blinking; LONG-RANGE ELECTRON; CHARGE-TRANSFER; HOLE-TRANSFER; DISTANCE; DYNAMICS; FLUORESCENCE; KINETICS; ENERGY; BASES;
D O I：
10.1246/bcsj.20220220
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Current understanding of electron transfer (ET) kinetics is largely based on ensemble measurements that obscure the underlying single-molecule behavior. We previously reported systematic distance-dependent single molecule ET measure-ments that show a large heterogeneity. Here we study and dis-cuss this heterogeneity in more detail and suggest that it is a rather fundamental phenomenon that is difficult to explain solely by the distribution of DNA conformations. This hetero-geneity may arise from the uniqueness of each molecule, or it may reflect the uncertainty of ET kinetics.
引用
收藏
页码：1697 / 1702
页数：6
相关论文
共 40 条
  • [1] Chemically-induced redox switching of a metalloprotein reveals thermodynamic and kinetic heterogeneity, one molecule at a time
    Akkilic, Namik
    van der Grient, Fenna
    Kamran, Muhammad
    Sanghamitra, Nusrat J. M.
    [J]. CHEMICAL COMMUNICATIONS, 2014, 50 (93) : 14523 - 14526
  • [2] Long-range electron and excitation energy transfer in donor-bridge-acceptor systems
    Albinsson, Bo
    Martensson, Jerker
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS, 2008, 9 (03) : 138 - 155
  • [3] Luminescence quenching of ruthenium(II)-tris(phenanthroline) by cobalt(III)-tris(phenanthroline) bound to the surface of starburst dendrimers
    ben-Avraham, D
    Schulman, LS
    Bossmann, SH
    Turro, C
    Turro, NJ
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (26): : 5088 - 5093
  • [4] Molecular-wire behaviour in p-phenylenevinylene oligomers
    Davis, WB
    Svec, WA
    Ratner, MA
    Wasielewski, MR
    [J]. NATURE, 1998, 396 (6706) : 60 - 63
  • [5] Distance-dependent activation energies for hole injection from protonated 9-amino-6-chloro-2-methoxyacridine into duplex DNA
    Davis, WB
    Hess, S
    Naydenova, I
    Haselsberger, R
    Ogrodnik, A
    Newton, MD
    Michel-Beyerle, ME
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (11) : 2422 - 2423
  • [6] Visualizing transient low-populated structures of RNA
    Dethoff, Elizabeth A.
    Petzold, Katja
    Chugh, Jeetender
    Casiano-Negroni, Anette
    Al-Hashimi, Hashim M.
    [J]. NATURE, 2012, 491 (7426) : 724 - +
  • [7] SEMICONDUCTIVITY OF ORGANIC SUBSTANCES .9. NUCLEIC ACID IN DRY STATE
    ELEY, DD
    SPIVEY, DI
    [J]. TRANSACTIONS OF THE FARADAY SOCIETY, 1962, 58 (470): : 411 - +
  • [8] Electron-transfer kinetics through nucleic acids untangled by single-molecular fluorescence
    Fan, Shuya
    Xu, Jie
    Osakada, Yasuko
    Hashimoto, Katsunori
    Takayama, Kazuya
    Natsume, Atsushi
    Hirano, Masaki
    Maruyama, Atsushi
    Fujitsuka, Mamoru
    Kawai, Kumi
    Kawai, Kiyohiko
    [J]. CHEM, 2022, 8 (11): : 3109 - +
  • [9] Architecture of the photosynthetic oxygen-evolving center
    Ferreira, KN
    Iverson, TM
    Maghlaoui, K
    Barber, J
    Iwata, S
    [J]. SCIENCE, 2004, 303 (5665) : 1831 - 1838
  • [10] The roles of structural dynamics in the cellular functions of RNAs
    Ganser, Laura R.
    Kelly, Megan L.
    Herschlag, Daniel
    Al-Hashimi, Hashim M.
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2019, 20 (08) : 474 - 489
1234