Prediction and verification of nonlinear sleep spindle harmonic oscillations

被引：32

作者：

Abeysuriya, R. G. ^{[1
,2
,3
]}

Rennie, C. J. ^{[1
,2
]}

Robinson, P. A. ^{[1
,2
,3
]}

机构：

[1] Univ Sydney, Sch Phys, Sydney, NSW 2006, Australia

[2] Univ Sydney, Sydney Med Sch Western, Brain Dynam Ctr, Westmead, NSW 2145, Australia

[3] Ctr Integrated Res & Understanding Sleep, Glebe, NSW 2037, Australia

来源：

JOURNAL OF THEORETICAL BIOLOGY | 2014年 / 344卷

基金：

澳大利亚研究理事会; 英国医学研究理事会;

关键词：

EEG; Neurophysiology; Neural field theory; ELECTRICAL-ACTIVITY; CEREBRAL-CORTEX; EEG; DYNAMICS; MODEL; PARAMETERS; MECHANISMS; THALAMUS; SPECTRA; STATES;

D O I：

10.1016/j.jtbi.2013.11.013

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This paper examines nonlinear effects in a neural field model of the corticothalamic system to predict the EEG power spectrum of sleep spindles. Nonlinearity in the thalamic relay nuclei gives rise to a spindle harmonic visible in the cortical EEG. By deriving an analytic expression for nonlinear spectrum, the power in the spindle harmonic is predicted to scale quadratically with the power in the spindle oscillation. By isolating sleep spindles from background sleep in experimental EEG data, the spindle harmonic is directly observed. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：70 / 77

页数：8

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