Reversal of enantioselectivity in the asymmetric rhodium- versus iridium-catalyzed hydroboration of meso substrates

被引：77

作者：

Luna, AP

Bonin, M

Micouin, L

Husson, HP

机构：

[1] CNRS, UMR 8638, Chim Therapeut Lab, F-75270 Paris 06, France

[2] Univ Paris 05, Fac Sci Pharmaceut & Biol, F-75270 Paris, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 41期

关键词：

D O I：

10.1021/ja026714m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Ir-catalyzed asymmetric hydroboration of bicyclic hydrazines with ee and chemical yields up to 64% is reported. The switch from rhodium to iridium leads systematically to opposite enantiomers in this desymmetrization reaction. Copyright © 2002 American Chemical Society.

引用

收藏

页码：12098 / 12099

页数：2

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