Progressive destruction of jaws caused by the delayed treatment of Langerhans cell histiocytosis in a 2-year-old boy: A case report

被引:2
作者
Meng, Mingmei [1 ,2 ,3 ]
Zhang, Qiong [1 ,2 ,3 ]
Zhou, Xuedong [1 ,2 ,4 ]
Zou, Jing [1 ,2 ,3 ]
机构
[1] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, 14,3rd Sect,Ren Min South Rd, Chengdu 610041, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, 14,3rd Sect,Ren Min South Rd, Chengdu 610041, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp Stomatol, Dept Pediat Dent, 14,3rd Sect,Ren Min South Rd, Chengdu 610041, Sichuan, Peoples R China
[4] Sichuan Univ, West China Hosp Stomatol, Dept Cariol & Endodont, 14,3rd Sect,Ren Min South Rd, Chengdu 610041, Sichuan, Peoples R China
关键词
Langerhans cell histiocytosis; Jaw; Cone beam CT; Bone destruction; EOSINOPHILIC GRANULOMA; MANIFESTATIONS;
D O I
10.1007/s11282-022-00606-1
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Langerhans cell histiocytosis (LCH) is a disease with varied clinic manifestations. The oral symptoms and signs of LCH localized to the jaws are nonspecific, which may lead to misdiagnosis of this disease. The purpose of this paper was to present the case of a 2-year, 4-month-old LCH patient with progressive destruction of jaws caused by the delayed treatment due to the global outbreak of COVID-19. The cone beam CT analysis after an interval of 6 months reminded us the great significance of early diagnosis and treatment of LCH.
引用
收藏
页码:433 / 437
页数:5
相关论文
共 16 条
[1]   Langerhans-Cell Histiocytosis [J].
Allen, Carl E. ;
Merad, Miriam ;
McClain, Kenneth L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (09) :856-868
[2]   Potential clinical implications of BRAF mutations in histiocytic proliferations [J].
Bubolz, Anna-Maria ;
Weissinger, Stephanie E. ;
Stenzinger, Albrecht ;
Arndt, Annette ;
Steinestel, Konrad ;
Bruederlein, Silke ;
Cario, Holger ;
Lubatschofski, Anneli ;
Welke, Claudia ;
Anagnostopoulos, Ioannis ;
Barth, Thomas F. E. ;
Beer, Ambros J. ;
Moeller, Peter ;
Gottstein, Martin ;
Viardot, Andreas ;
Lennerz, Jochen K. .
ONCOTARGET, 2014, 5 (12) :4060-4070
[3]   Primary Oro-Facial Manifestations of Langerhans Cell Histiocytosis in Pediatric Age: A Bi-Institutional Retrospective Study on 45 Cases [J].
Capodiferro, Saverio ;
Tempesta, Angela ;
Limongelli, Luisa ;
Ingravallo, Giuseppe ;
Maiorano, Eugenio ;
Sfasciotti, Gian Luca ;
Bossu, Maurizio ;
Polimeni, Antonella ;
Favia, Gianfranco .
CHILDREN-BASEL, 2020, 7 (09)
[4]  
Chou T., 1987, WRITING GROUP HISTIO, V1, P9
[5]   Unisystem Langerhans cell histiocytosis in maxillofacial region in pediatrics: comprehensive and systematic review [J].
Chugh, Ankita ;
Kaur, Amanjot ;
Kumar Patnana, Arun ;
Kumar, Pravin ;
Chugh, Vinay Kumar .
ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG, 2021, 25 (04) :429-444
[6]   Langerhans cell histiocytosis: A case report with oral manifestations and the role of pediatric dentists in the diagnosis [J].
Hammouri, Eman Hussein ;
Sweidan, Hala Antoun ;
AShokaibi, Omar ;
Al Omari, Leen .
CLINICAL CASE REPORTS, 2020, 8 (03) :545-549
[7]   BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy [J].
Heritier, Sebastien ;
Emile, Jean-Francois ;
Barkaoui, Mohamed-Aziz ;
Thomas, Caroline ;
Fraitag, Sylvie ;
Boudjemaa, Sabah ;
Renaud, Florence ;
Moreau, Anne ;
Peuchmaur, Michel ;
Chassagne-Clement, Catherine ;
Dijoud, Frederique ;
Rigau, Valerie ;
Moshous, Despina ;
Lambilliotte, Anne ;
Mazingue, Francoise ;
Kebaili, Kamila ;
Miron, Jean ;
Jeziorski, Eric ;
Plat, Genevieve ;
Aladjidi, Nathalie ;
Ferster, Alina ;
Pacquement, Helene ;
Galambrun, Claire ;
Brugieres, Laurence ;
Leverger, Guy ;
Mansuy, Ludovic ;
Paillard, Catherine ;
Deville, Anne ;
Armari-Alla, Corinne ;
Lutun, Anne ;
Gillibert-Yvert, Marion ;
Stephan, Jean-Louis ;
Cohen-Aubart, Fleur ;
Haroche, Julien ;
Pellier, Isabelle ;
Millot, Frederic ;
Lescoeur, Brigitte ;
Gandemer, Virginie ;
Bodemer, Christine ;
Lacave, Roger ;
Helias-Rodzewicz, Zofia ;
Taly, Valerie ;
Geissmann, Frederic ;
Donadieu, Jean .
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (25) :3023-+
[8]  
Kumar Y Pavan, 2015, Contemp Clin Dent, V6, P432, DOI 10.4103/0976-237X.161912
[9]   Childhood Langerhans cell histiocytosis: a disease with many faces [J].
Leung, Alexander K. C. ;
Lam, Joseph M. ;
Leong, Kin Fon .
WORLD JOURNAL OF PEDIATRICS, 2019, 15 (06) :536-545
[10]   Recent advances in Langerhans cell histiocytosis [J].
Morimoto, Akira ;
Oh, Yukiko ;
Shioda, Yoko ;
Kudo, Kazuko ;
Imamura, Toshihiko .
PEDIATRICS INTERNATIONAL, 2014, 56 (04) :451-461