Study of the temporal distribution of the adhesion-spreading events of liposomes on a mercury electrode

被引:8
作者
Hernandez, Victor Agmo [3 ]
Milchev, Alexander [2 ]
Scholz, Fritz [1 ]
机构
[1] Ernst Moritz Arndt Univ Greifswald, Inst Biochem, D-17487 Greifswald, Germany
[2] Bulgarian Acad Sci Acad G, Rostislaw Kaischew Inst Phys Chem, Sofia 1113, Bulgaria
[3] Uppsala Univ, Dept Phys & Analyt Chem, Div Phys Chem, S-75123 Uppsala, Sweden
关键词
Liposomes; Chronoamperometry; Adhesion spreading; Mercury electrode; DMPC; Metal nucleation; PEPTIDE MASTOPARAN-X; PHASE-COMPOSITION; DMPC LIPOSOMES; KINETICS; LAMELLARITY; CURVATURE; SURFACE; SIZE; VESICLES; FUSION;
D O I
10.1007/s10008-008-0770-5
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
The formal analysis of the mechanism of adhesion spreading of liposomes at mercury electrodes shares several characteristics with the mechanism of metal nucleation at electrodes. It is shown that the description of the temporal distribution of the adhesion-spreading events is similar to that of the temporal distribution of metal clusters. Both processes are stochastic in nature and can be described by the Poisson distribution. Using this approach, a previously proposed model for the overall adhesion-spreading mechanism, considering the formation of active sites on the liposome and the actual attachment of the liposomes to the mercury surface, is validated.
引用
收藏
页码:1111 / 1114
页数:4
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