Emerging drugs for acute ischemic stroke

被引:0
作者
Sicard, Kenneth M. [2 ]
Fisher, Marc [1 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Neurol, Worcester, MA 01655 USA
[2] St Vincent Hosp, Worcester Med Ctr, Dept Internal Med, Woprcester, MA 01608 USA
关键词
albumin; CT; diffusion; erythropoietin; G-CSF; magnesium; MERCI retriever; MRI; neuroprotection; penumbra; perfusion; reperfusion; thrombolysis; tPA; COLONY-STIMULATING FACTOR; FOCAL CEREBRAL-ISCHEMIA; TISSUE-PLASMINOGEN ACTIVATOR; MARKED NEUROPROTECTIVE EFFICACY; ALIAS PILOT TRIAL; ALBUMIN THERAPY; MAGNESIUM-SULFATE; THROMBOLYTIC THERAPY; ARTERY-OCCLUSION; DOSE-ESCALATION;
D O I
10.1517/14728210902748365
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Stroke is no longer an untreatable condition, and its management is changing rapidly as new developments appear for acute treatments. The objective of this article is to provide a concise introduction to the pathophysiology and existing treatments for stroke, as well as discussing current research goals and interventions under evaluation, along with potential development issues. it will end with the authors' interpretations of the presented material and their opinions about where the field is going, or should go, in the coming years. The material herein is derived from current literature and expert opinion. Overall, the most important findings are that future advances in stroke treatment will probably include combination therapies that will be administered in specialized stroke care units to maximize patient outcome.
引用
收藏
页码:33 / 42
页数:10
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