Identification of prognostic factors in post-transplantation lymphoproliferative disorders

被引:0
作者
Choquet, S
Levy, V
Leblond, V
机构
[1] Hop Versailles, Serv Hematol Clin, F-78157 Le Chesnay, France
[2] Hop St Louis, INSERM, ERM 321, F-75010 Paris, France
[3] Hop La Pitie Salpetriere, Serv Hematol Clin, F-75013 Paris, France
关键词
post-transplantation lymphoproliferative disorder; prognostic factor; organ transplantation; IPI;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Post-transplantation lymphoproliferative disorders (PTLD) represent a severe complication of organ transplantation, so the determination of prognostic factors for the response and the survival is of major interest. Studies oil PTLD are hindered by the small number of cases, explaining the conflicting published results. In order to identify prognostic factors in this kind of disease, 67 patients have been analyzed in a retrospective multicenter study. A new index is proposed to assess the survival probability, it is composed of two factors: the performance status (PS less than or equal to 1 versus 2-3) and the number of involved sites (1 versus > 1). This index seems to be more accurate in PTLD than the IPI, the reference in immunocompetent patients with non Hodgkin lymphomas. However. a similar analysis in a more homogeneous population remains necessary.
引用
收藏
页码:373 / 378
页数:6
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