Transformation of 4-oxo-4H-[1]-benzopyran-3-carboxaldehydes into pyrazolo[3,4-b]pyridines

被引：16

作者：

Stankovicova, Henrieta

Gaplovsky, Anton

Lacova, Margita

Chovancova, Jarmila

Puchala, Agnieszka

机构：

[1] Comenius Univ, Fac Nat Sci, Inst Chem, Bratislava 84215, Slovakia

[2] Comenius Univ, Fac Nat Sci, Dept Organ Chem, Bratislava 84215, Slovakia

[3] Swietokrzyska Univ, Inst Chem, PL-25020 Kielce, Poland

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 43卷 / 04期

关键词：

D O I：

10.1002/jhet.5570430405

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 6-methyl-4-oxo-4H-[1]-benzopyran-3-carboxaldehyde 1 with 5-amino-3-methyl-1-phenylpyrazole 2 in alcoholic reaction media in the presence of 4-toluenesulfonic acid as catalyst afforded 5-(2-hydroxy-5-methylbenzoyl)-3-methyl-l-phenyl-1H-pyrazolo[3,4-b]pyridine 3 and 2-methoxy-6-methyl-3(3-methyl-1-phenylpyrazol-5-ylaminomethylene)chroman-4-one 7. We explain the mechanism of formation of both products on the basis of kinetic study of individual reaction steps.

引用

页码：843 / 848

页数：6

共 21 条

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