Rapid detection of the factor V Leiden mutation by real-time PCR with TaqMan minor groove binder probes

被引:12
作者
Luderer, R
Verheul, A
Kortlandt, W
机构
[1] Diakonessenshuis Utrecht, Unit Mol Diagnost, NL-3582 KE Utrecht, Netherlands
[2] Diakonessenshuis Utrecht, Dept Clin Chem, NL-3582 KE Utrecht, Netherlands
关键词
D O I
10.1373/clinchem.2003.028845
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
引用
收藏
页码:787 / 788
页数:2
相关论文
共 10 条
[1]  
Happich D, 1999, THROMB HAEMOSTASIS, V82, P1294
[2]  
KOELEMAN BPC, 1994, BLOOD, V84, P1031
[3]   Solution structure of a highly stable DNA duplex conjugated to a minor groove binder [J].
Kumar, S ;
Reed, MW ;
Gamper, HB ;
Gorn, VV ;
Lukhtanov, EA ;
Foti, M ;
West, J ;
Meyer, RB ;
Schweitzer, BI .
NUCLEIC ACIDS RESEARCH, 1998, 26 (03) :831-838
[4]   3′-minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures [J].
Kutyavin, IV ;
Afonina, IA ;
Mills, A ;
Gorn, VV ;
Lukhtanov, EA ;
Belousov, ES ;
Singer, MJ ;
Walburger, DK ;
Lokhov, SG ;
Gall, AA ;
Dempcy, R ;
Reed, MW ;
Meyer, RB ;
Hedgpeth, J .
NUCLEIC ACIDS RESEARCH, 2000, 28 (02) :655-661
[5]  
Lay MJ, 1997, CLIN CHEM, V43, P2262
[6]   WORLD DISTRIBUTION OF FACTOR-V LEIDEN [J].
REES, DC ;
COX, M ;
CLEGG, JB .
LANCET, 1995, 346 (8983) :1133-1134
[7]   HIGH-RISK OF THROMBOSIS IN PATIENTS HOMOZYGOUS FOR FACTOR-V LEIDEN (ACTIVATED PROTEIN-C RESISTANCE) [J].
ROSENDAAL, FR ;
KOSTER, T ;
VANDENBROUCKE, JP ;
REITSMA, PH .
BLOOD, 1995, 85 (06) :1504-1508
[8]  
SANDERS SJ, 2000, MOL CELL PROBE, V14, P249
[9]  
van den Bergh FAJTM, 2000, CLIN CHEM, V46, P1191
[10]   A method for homogeneous color-compensated genotyping of factor V (G1691A) and methylenetetrahydrofolate reductase (C677T) mutations using real-time multiplex fluorescence PCR [J].
von Ahsen, N ;
Oellerich, M ;
Schütz, E .
CLINICAL BIOCHEMISTRY, 2000, 33 (07) :535-539