Septic shock in canine babesiosis

被引:57
作者
Matijatko, Vesna [1 ]
Kis, Ivana [1 ]
Torti, Marin [1 ]
Brkljacic, Mirna [1 ]
Kucer, Nada [1 ]
Rafaj, Renata Baric [2 ]
Grden, Darko [1 ]
Zivicnjak, Tanja [3 ]
Mrljak, Vladimir [1 ]
机构
[1] Univ Zagreb, Clin Internal Dis, Fac Vet Med, Zagreb 10000, Croatia
[2] Univ Zagreb, Dept Chem & Biochem, Fac Vet Med, Zagreb 10000, Croatia
[3] Univ Zagreb, Dept Parasitol, Fac Vet Med, Zagreb 10000, Croatia
关键词
Babesiosis; Dog; Septic shock; Sepsis; SIRS; MODS; Blood pressure; INFLAMMATORY RESPONSE SYNDROME; NECROSIS-FACTOR-ALPHA; NITRIC-OXIDE; CLINICOPATHOLOGICAL FINDINGS; FALCIPARUM-MALARIA; ORGAN FAILURE; SOUTH-AFRICA; DOGS; SEPSIS; COMPLICATION;
D O I
10.1016/j.vetpar.2009.03.011
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The records of all canine patients (86) that had been diagnosed with babesiosis and that were admitted to the Clinic for Internal Diseases, Faculty of Veterinary Medicine, Zagreb from January 2007 to December 2007 were reviewed retrospectively. All dogs that had been diagnosed with canine babesiosis and that had systemic inflammatory response syndrome (SIRS) followed by multiple organ dysfunction syndrome (MODS), and refractory hypotension, were included in this study. Of 86 patients diagnosed with canine babesiosis that were admitted during the study period, 10 had evidence of septic shock and were included in this study. Seven of the 10 dogs had a level of parasitaemia above 1%,with the highest level being 20.2%, seven of the 10 dogs were anaemic and three of the 10 dogs were leucopoenic. Thrombocytopenia was present in nine dogs. Hypoglycaemia was noted in two dogs, and bilirubinaemia in nine dogs. Four patients had involvement of two organs, five had involvement of three organs, and one had involvement of four organs. The organ that was most frequently involved was the kidney (nine cases). Central nervous system dysfunction was the rarest complication noted (one case). The mortality rate in non-septic shock canine babesiosis was 2.6%. All dogs that developed septic shock died between the first and the fourth day after admission. The 100% mortality rate that is reported here reflects the fact that in cases in which progression of the inflammatory response leads to the development of septic shock, an unfavourable outcome should be expected. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:263 / 270
页数:8
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