In vitro activity of Bay 12-8039, a new 8-methoxyquinolone

被引：81
作者：
Fass, RJ
机构：
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 08期
关键词：
D O I：
10.1128/AAC.41.8.1818
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
MICs of Bay 12-8039 and comparative antimicrobials mere determined for 820 recent clinical isolates. Ciprofloxacin was approximate to 2-fold more active than Bay 12-8039 and ofloxacin against Enterobacteriaceae and approximate to 8-fold more active against Pseudomonas aeruginosa, Bay 12-8039 was approximate to 2- to 16-fold more active than ciprofloxacin and ofloxacin against nonfermenters (except P. aeruginosa), streptococci, streptococci, enterococci, and anaerobes. As determined bg regression analysis, there mas a high degree of correlation among quinolone MICs.
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页码：1818 / 1824
页数：7
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