When to rule out COVID-19: How many negative RT-PCR tests are needed?

被引：3
|
作者：
Isikbay, Masis [1 ]
Henry, Travis S. [1 ]
Frank, James A. [2 ]
Hope, Michael D. [1 ,3 ]
机构：
[1] Univ Calif San Francisco, Dept Radiol & Biomed Imaging, 505 Parnassus Ave,M-396, San Francisco, CA 94143 USA
[2] San Francisco VA Med Ctr, Dept Pulmonol Crit Care, San Francisco, CA USA
[3] San Francisco VA Med Ctr, Dept Radiol, San Francisco, CA USA
来源：
RESPIRATORY MEDICINE CASE REPORTS | 2020年 / 31卷
关键词：
COVID-19; infection; RT-PCR; CT Chest; Sensitivity; Specificity; Prevalence; Negative predictive value; False negative rate; CHEST CT;
D O I：
10.1016/j.rmcr.2020.101192
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. It has become commonplace for a patient under investigation (PUI) to repeatedly test negative but have imaging findings that are consistent with COVID-19. This raises the question of when the treating team should entertain alternative diagnoses. We present such a case to help provide a framework for how to weigh repeatedly negative test results in clinical decision making when there is ongoing concern for COVID-19.
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页数：3
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